在Jawer Kotok叶(Plectranthus Scutellarioides L. R.Br.)标准提取物速溶颗粒配方中添加氯化钠作为去味剂对专家小组成员口味反应的影响

M. Hamidah, Moelyono Moektiwardoyo, Marline Abdassah Bratadiredja
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引用次数: 0

摘要

Jawer Kotok Leaves(Plectranthus scutellarioides (L.) R.Br.)是一种印度尼西亚本地植物,科学证明它具有消炎特性,尤其是在民族药学和药理学领域。根据以往的研究,Jawer Kotok 叶在帮助愈合卡拉胶诱导的雄性白鼠(Ratus norwegicus)脚底水肿伤口方面具有卓越的潜力。为了充分发挥 Jawer Kotok 叶的潜力,增加社区对传统药物的使用,我们制作了一种速溶颗粒形式的实用制剂。速溶颗粒制剂有几个优点,即可以单位剂量包装、流动性好、易于吞咽、在热水或冷水中保持稳定、溶解速度快,并且容易与染料、香精和其他药物成分结合,因此很容易被消费者接受。为了获得能被消费者接受的最佳配方,本研究制作了 4 种不同的配方。所面临的问题之一是颚齿科托叶提取物的嚼味,因此,在本研究中,氯化钠作为嚼味去除剂对颚齿科托叶(Plectranthus scutellarioides (L.) R.Br.)标准化提取物速溶颗粒配方的影响受到了小组成员的喜爱。这些参数包括质地、颜色、味道和香气。使用的材料是经过标准化的乙醇提取物。根据已进行的统计测试,添加氯化钠对减少颚儿科多克叶速溶颗粒的涩味没有显著影响。最佳配方是配方 3,因为它具有良好的物理特性,与其他配方相比,它的 "相似 "反应最多。配方 3 的成分包括粘性提取物 16.8%、PVP 4%、乳糖 56.5%、赤藓糖醇 10%、甜叶菊苷 2.5%、黄原胶 0.2%和麦芽糊精 10%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pengaruh Penambahan Natrium Klorida Sebagai Penghilang Rasa Kelat pada Formula Granul Instan Ekstrak Terstandar Daun Jawer Kotok (Plectranthus Scutellarioides L. R.Br.) Terhadap Respon Kesukaan Panelis
Jawer Kotok Leaves (Plectranthus scutellarioides (L.) R.Br.) is a native Indonesian plant that has been scientifically proven to have anti-inflammatory properties, especially in the fields of ethnopharmacognosy and pharmacology. Based on previous studies, Jawer Kotok Leaves has excellent potential in helping heal oedema wounds on the soles of the feet of male white rats (Ratus norwegicus) wistar strain induced by carrageenan. To optimize the potential of Jawer Kotok Leaves and increase the use of traditional medicine among the community, a practical preparation in the form of instant granules is made. Instant granule preparations have several advantages, namely that they can be packaged in one unit dose, have good flow properties, are easy to swallow, remain stable in hot or cold water, dissolve quickly and are easily combined with dyes, flavors, and other pharmaceutical ingredients so that they are easily accepted by consumers. To get the best formula that can be accepted by consumers, this study made 4 variations of the formula. One of the problems faced is the chewy taste of jawer kotok leaf extract, therefore in this study the effect of sodium chloride as a chewy taste remover on the instant granule formula of standardized extract of jawer kotok leaves (Plectranthus scutellarioides (L.) R.Br.) on the panelists' favorite response. The parameters seen are texture, color, taste and aroma. The material used is ethanol extract that has been standardized. Based on statistical tests that have been carried out, the addition of NaCl does not provide a significant difference to the reduction of astringent taste in instant granules of jawer kotok leaves. The best formula is Formula 3 because it has good physical quality and gives the most "like" response compared to other formulas. The components of formula 3 consisted of viscous extract 16.8%, PVP 4%, lactose 56.5%, erythritol 10%, stevia glycoside 2.5%, xanthan gum 0.2% and maltodextrin 10%.
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