芫荽籽油的结构和抗菌活性表征

Q3 Pharmacology, Toxicology and Pharmaceutics
Wijdan Amer Ibrahim, Ekhlas Abdallah Hassan, W. Al-Zuhairi
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引用次数: 0

摘要

本研究旨在研究芫荽籽油(CSO)中生物活性成分的结构及其抗菌作用。首先,利用傅立叶变换红外光谱和紫外-可见光谱等多种光谱技术进行了结构检测,这些技术对于确定芫荽籽油中的取代基、官能团和共轭双键的存在非常重要。从傅立叶变换红外光谱中可以看到与芳樟醇和癸烯醇 CSO 的主要成分有关的各种尖锐、强烈和微弱的峰。紫外可见光谱的结果证实了芳樟醇是主要化合物,同时还发现了共轭双键。此外,还研究了 CSO 对各种细菌的抗微生物活性。观察到了很强的抑菌作用,尤其是对金黄色葡萄球菌,平均抑菌区为 18 毫米。从 CSO 的结构特征中还发现,芳樟醇的存在是其潜在抗菌活性的原因。这项研究的主要发现是,CSO 甚至对耐甲氧西林的金黄色葡萄球菌也有抗菌活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Characterization of Structural, Antimicrobial Activity, of Coriander Seed Oil
This study was aimed to investigate the structure of bioactive components of Coriander Seed Oil (CSO) and their antimicrobial effects. Initially, the structural examination was conducted using various spectroscopic techniques, such as FTIR, and UV-visible spectroscopy, which are important in determining substituents, functional groups, and the presence of conjugated double bonds in CSO. From the FTIR spectra, a variety of sharp, strong, and weak peaks were specified relating to the main components of Linalol, and Decenolin CSO. The results of UV-visible spectroscopy confirmed the presence of Linalool as a major compound, and conjugated double bonds were also found. Furthermore, anti- microbial activity of CSO was studied against various types of bacteria. Strong bacterial inhibitory effects were observed, especially against S. aureus, with an average inhibition zone of 18 mm. It was also found from the structural characterization of CSO that the existence of Linalol is responsible for potential antibacterial activity. The main observation of this work is that CSO has antimicrobial activity even against methicillin-resistant Staphylococcus aureus.
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来源期刊
Research Journal of Pharmacy and Technology
Research Journal of Pharmacy and Technology Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
CiteScore
1.40
自引率
0.00%
发文量
0
期刊介绍: Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.
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