地震诱发遗传性血管性水肿患者急性发作

Dicle Tıp Dergisi Pub Date : 2024-01-24 DOI:10.5798/dicletip.1451503

Müge Erbay, Can Tuzer, Merve Erkoç, Merve Erkoç

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摘要

目标2023 年 2 月 6 日，土耳其东南部地区发生了 7.7 级和 7.6 级两次大地震。遗传性血管性水肿（HAE）是一种遗传性疾病，可因心理因素和身体创伤而恶化。我们的研究旨在评估地震及地震相关焦虑、抑郁和压力因素对 HAE 患者的影响。研究方法采用抑郁-焦虑-压力量表（DASS-21）对患者的心理健康状况进行评估。结果：研究共纳入 63 名 HAE 患者。半数以上（33 人，52.4%）为女性，年龄中位数为 31（26-42）岁。DASS-压力、DASS-焦虑和DASS-抑郁评分显示，分别有25（39.7%）、37（58.7%）和32（50.8%）名患者存在异常压力、焦虑和抑郁状态。震后发作和注射 icatibant 的人数明显高于震前（p

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Earthquake as a Trigger of Acute Attacks in People with Hereditary Angioedema

Objectives: Two major earthquakes with 7.7 and 7.6 magnitudes struck the southeastern region of Turkey on February 6th, 2023. Hereditary angioedema (HAE) is an inherited disease that can be worsened by psychological factors and physical trauma.Our study aimed to evaluate the effect of earthquake and earthquake-related anxiety, depression and stress factors in HAE patients. Methods: The study was conducted on patients with HAE who are located in the southeastern region of Turkey.The mental-health-status was evaluated with Depression-Anxiety-Stress-Scale(DASS-21). Results: Sixty-three HAE patients were includedin the study. More than half(n:33, 52.4%) were female andthe median age was 31(26-42) years. DASS-Stress, DASS-Anxiety,and DASS-Depression scores revealed that 25(39.7%), 37(58.7%) and 32(50.8%) patients had abnormal stress, anxiety and depression status, respectively. The numbers of post-earthquake attacks and icatibant injections were significantly higher than the ones in the pre-earthquake period(p

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