头胎CRL(头臀距)与NT(颈项透明层)测量值的比值在预测早发胎儿生长受限(FGR)中的作用

Refaettin Şahi̇n, Atakan Tanacan, Hakkı Şerbetçi̇, Osman Onur Özkavak, Murat Haksever, Mehmet Utku Başarir, Özgür Kara, Dilek Sahi̇n
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引用次数: 0

摘要

目的我们的目的是评估首胎 CRL(冠状脊长)测量值与 NT(颈项透明带)测量值的比值在预测早期胎儿生长受限(FGR)中的作用,并为现有文献提供参考。研究方法在本病例对照研究中,早发 FGR 胎儿与频率匹配的低风险对照组进行了比较。这项研究于 2020 年至 2023 年期间在安卡拉比尔肯特市医院围产期门诊进行。对早发FGR孕妇(39人)和无FGR孕妇(50人)的母体年龄、孕周、奇偶数、冠臀长(CRL)和颈项透明层(NT)测量结果进行了比较。结果参与研究的 FGR 孕妇的平均年龄为(27.1±0.8)岁,无 FGR 孕妇的平均年龄为(26.3±0.6)岁,两组间差异无统计学意义(P=0.4)。有FGR的孕妇的平均CRL为(54.98±1.08)mm,无FGR的孕妇的平均CRL为(56.99±1.11)mm,两组间无明显差异(P=0.2)。FGR组的NT值为(1.11±0.04)毫米,无FGR组为(1.13±0.02)毫米,两组间无明显差异(P=0.73)。早发FGR组的平均CRL/NT比值为(52.00±2.33),无FGR组为(51.46±1.48),两组间差异无统计学意义(P=0.83)。如果对早发 FGR 组进行内部评估,其诊断时的平均年龄为(31.7±0.3)周。诊断时的 EFW 平均百分位数为 4.5±0.6,ac 百分位数为 2.9±0.4。平均脐动脉收缩压/舒张压比值(UA-SD)为(2.9±0.16),平均脐动脉搏动指数(UA-PI)为(1.02±0.05)。结论冠状脊柱长度与颈部透亮度的比值对预测早发FGR并无临床意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Erken başlangıçlı fetal büyüme kısıtlamasını (FGR) öngörmede ilk trimester CRL (baş popo mesafesi) ölçümünün NT (ense saydımlığı) ölçümlerine oranının rolü
Objective: Our aim is to evaluate the role of the ratio of first-trimester CRL (crown rump length) measurement to NT (nuchal translucency) measurements in predicting early-onset fetal growth restriction (FGR) and to contribute to the existing literature. Methods: In the present case-control study, fetuses with early-onset FGR were compared to a frequency matched low risk control group. This study was conducted in the perinatology clinic of Ankara Bilkent City Hospital between 2020 and 2023. Maternal age, gravidity, parity, crown-rump length (CRL), and nuchal translucency (NT) measurements were compared between pregnant women with early onset FGR (n=39) and pregnant women without FGR (n=50). Results: The mean age of pregnant women with FGR who participated in the study was 27.1±0.8, and the mean age of pregnant women without FGR was 26.3±0.6, and no statistically significant difference was found between the two groups (p=0.4)). Mean CRL was 54.98±1.08 mm in the group with FGR and 56.99±1.11 mm in the group without FGR; there was no significant difference between the two groups (p=0.2). The NT value was 1.11 ± 0.04 mm in the FGR group and 1.13 ± 0.02 mm in the without FGR group, there was no significant difference between the two groups (p=0.73). The mean CRL/NT ratio was 52.00±2.33 in the group with early onset FGR and 51.46±1.48 in the group without FGR and there was no statistically significant difference between the two groups (p=0.83). When the early developing FGR group is evaluated within itself, the mean age at diagnosis was 31.7±0.3 weeks. EFW mean percentile at diagnosis was 4.5±0.6 and ac percentile was 2.9±0.4. The mean umbilical artery systole/diastole ratio (UA-SD) was 2.9±0.16 and the mean umbilical artery pulsatility index (UA-PI) was 1.02±0.05. Conclusion: Crown-rump length to nuchal translucency ratio is not clinically useful to predict early-onset FGR.
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