头孢吡肟诱发的非惊厥性癫痫状态

The Southwest Respiratory and Critical Care Chronicles Pub Date : 2024-01-29 DOI:10.12746/swrccc.v12i50.1277

Walter R Duarte-Celada, Samathorn Thakolwiboon, Jie Pan, Tulio Bueso, Jannatul Ferdous

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摘要

头孢吡肟诱发的非惊厥性癫痫状态（NCSE）可发生在高龄、肾功能受损和既往患有中枢神经系统疾病的患者身上。其临床表现从意识模糊、缄默、意识水平下降到昏迷不等。典型的脑电图（EEG）表现为1-3赫兹的全身性尖波和波状放电。我们介绍了 4 例头孢吡肟诱发的 NCSE 患者的病例系列，包括临床表现和脑电图检查结果。脑电图检查应成为使用这种抗生素的患者急性意识模糊状态检查的一部分，医生应注意这种不常见的并发症。关键词非惊厥性癫痫状态头孢吡肟意识模糊肢体缄默脑电图

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Cefepime-induced non-convulsive status epilepticus

Cefepime-induced non-convulsive status epilepticus (NCSE) can develop in patients with advanced age, renal impairment, and previous central nervous system disorders. Its clinical presentation varies from confusion, mutism, and decreased level of consciousness to coma. The typical electroencephalogram (EEG) findings are generalized spike and wave discharges of 1-3 Hz. We present a case series of 4 patients with cefepime-induced NCSE, including the clinical presentation and EEG findings. Electroencephalograms should be part of the workup of acute confusional state in patients on this antibiotic, and physicians should be aware of this uncommon complication. Keywords: Non-convulsive status epilepticus, cefepime, confusion, mutism, electroencephalogram.

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The Southwest Respiratory and Critical Care Chronicles

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