2 型糖尿病患者尿白蛋白排泄量与营养状况之间的关系

IF 0.2 Q4 UROLOGY & NEPHROLOGY
Minh Pham Duc, Kien Xuan Nguyen, Tien Tran Viet, Tuan Dinh Le, Nga Phi Thi Nguyen, Nui Minh Nguyen, Thuc Luong Cong, Son Tien Nguyen, Ba Van Nguyen, An Van Nguyen, Thang Ba Ta
{"title":"2 型糖尿病患者尿白蛋白排泄量与营养状况之间的关系","authors":"Minh Pham Duc, Kien Xuan Nguyen, Tien Tran Viet, Tuan Dinh Le, Nga Phi Thi Nguyen, Nui Minh Nguyen, Thuc Luong Cong, Son Tien Nguyen, Ba Van Nguyen, An Van Nguyen, Thang Ba Ta","doi":"10.34172/jrip.2023.32179","DOIUrl":null,"url":null,"abstract":"Introduction: Diet plays an important role in blood glucose control and management of vascular complications in patients with type 2 diabetes mellitus (T2DM). Excess food intake can be a burden to kidney function and, therefore increase diabetic nephropathy in T2DM. Objectives: To determine the nutritional status and the association between nutrition regime and urinary albumin excretion in patients with T2DM in Vietnam. Patients and Methods: The study was carried out on 594 outpatients with T2DM at military hospital 103, Hanoi, Vietnam from December 2020 to April 2021. Nutrient regime was calculated based on the guidelines of Vietnam national institute of nutrition. Urinary albumin concentrations were measured by enzymatic turbidimeter autoanalyzer. Results: Twenty-four hours nutrient intake is as follows: mean total calorie intake of 1913.72 ± 235.87 kcal; protein of 80.76 ± 14.56 g, fat of 51.10 ± 13.97 g, carbohydrate of 284.83 ± 47.71 g, fiber of 7.35 g (5.85-8.87). Calorie, protein, fat, and carbohydrate intakes per kilogram of body weight (BW) are lower in men compared with women. In the univariate analysis, urinary albumin concentrations correlated with 24-hour protein intake (r = 0.391, P=0.02). In the univariate linear regression analysis, urinary albumin significantly correlated with protein intake (standardized B=0.616, P=0.004); fat intake (standardized B=0.601, P=0.002); diabetes duration (standardized B=0.441, P=0.028), and energy intake (standardized B=- 0.467, P=0.039). Microalbuminuria (MAU) significantly correlated with protein intake (OR=1.042, P=0.006) and HbA1c (OR = 1.664, P=0.013). Conclusion: In patients with T2DM in Vietnam, 24-hour calory intake is 1913.72 ± 235.87 kcal, fat and carbohydrate intakes are within the normal range. Urinary albumin concentrations and MAU had a significant correlation with protein, fat and calory intakes.","PeriodicalId":16950,"journal":{"name":"Journal of Renal Injury Prevention","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The association between urinary albumin excretion and nutrient status in patients with type 2 diabetes mellitus\",\"authors\":\"Minh Pham Duc, Kien Xuan Nguyen, Tien Tran Viet, Tuan Dinh Le, Nga Phi Thi Nguyen, Nui Minh Nguyen, Thuc Luong Cong, Son Tien Nguyen, Ba Van Nguyen, An Van Nguyen, Thang Ba Ta\",\"doi\":\"10.34172/jrip.2023.32179\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Diet plays an important role in blood glucose control and management of vascular complications in patients with type 2 diabetes mellitus (T2DM). Excess food intake can be a burden to kidney function and, therefore increase diabetic nephropathy in T2DM. Objectives: To determine the nutritional status and the association between nutrition regime and urinary albumin excretion in patients with T2DM in Vietnam. Patients and Methods: The study was carried out on 594 outpatients with T2DM at military hospital 103, Hanoi, Vietnam from December 2020 to April 2021. Nutrient regime was calculated based on the guidelines of Vietnam national institute of nutrition. Urinary albumin concentrations were measured by enzymatic turbidimeter autoanalyzer. Results: Twenty-four hours nutrient intake is as follows: mean total calorie intake of 1913.72 ± 235.87 kcal; protein of 80.76 ± 14.56 g, fat of 51.10 ± 13.97 g, carbohydrate of 284.83 ± 47.71 g, fiber of 7.35 g (5.85-8.87). Calorie, protein, fat, and carbohydrate intakes per kilogram of body weight (BW) are lower in men compared with women. In the univariate analysis, urinary albumin concentrations correlated with 24-hour protein intake (r = 0.391, P=0.02). In the univariate linear regression analysis, urinary albumin significantly correlated with protein intake (standardized B=0.616, P=0.004); fat intake (standardized B=0.601, P=0.002); diabetes duration (standardized B=0.441, P=0.028), and energy intake (standardized B=- 0.467, P=0.039). Microalbuminuria (MAU) significantly correlated with protein intake (OR=1.042, P=0.006) and HbA1c (OR = 1.664, P=0.013). Conclusion: In patients with T2DM in Vietnam, 24-hour calory intake is 1913.72 ± 235.87 kcal, fat and carbohydrate intakes are within the normal range. Urinary albumin concentrations and MAU had a significant correlation with protein, fat and calory intakes.\",\"PeriodicalId\":16950,\"journal\":{\"name\":\"Journal of Renal Injury Prevention\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2024-01-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Renal Injury Prevention\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.34172/jrip.2023.32179\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Renal Injury Prevention","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34172/jrip.2023.32179","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0

摘要

简介饮食在 2 型糖尿病(T2DM)患者控制血糖和控制血管并发症方面发挥着重要作用。过多的食物摄入会对肾功能造成负担,从而加重 2 型糖尿病患者的糖尿病肾病。研究目的确定越南 T2DM 患者的营养状况以及营养制度与尿白蛋白排泄量之间的关系。患者和方法:研究于 2020 年 12 月至 2021 年 4 月在越南河内市第 103 军事医院对 594 名 T2DM 门诊患者进行了调查。营养方案根据越南国家营养研究所的指南计算。用酶联浊度仪自动分析仪测量尿白蛋白浓度。结果24 小时营养摄入量如下:平均总热量摄入量为(1913.72 ± 235.87)千卡;蛋白质(80.76 ± 14.56)克;脂肪(51.10 ± 13.97)克;碳水化合物(284.83 ± 47.71)克;纤维素(7.35)克(5.85-8.87)。与女性相比,男性每公斤体重(BW)的卡路里、蛋白质、脂肪和碳水化合物摄入量较低。在单变量分析中,尿白蛋白浓度与 24 小时蛋白质摄入量相关(r = 0.391,P=0.02)。在单变量线性回归分析中,尿白蛋白与蛋白质摄入量(标准化B=0.616,P=0.004)、脂肪摄入量(标准化B=0.601,P=0.002)、糖尿病病程(标准化B=0.441,P=0.028)和能量摄入量(标准化B=- 0.467,P=0.039)显著相关。微量白蛋白尿(MAU)与蛋白质摄入量(OR=1.042,P=0.006)和 HbA1c(OR=1.664,P=0.013)显著相关。结论越南 T2DM 患者的 24 小时热量摄入量为 1913.72 ± 235.87 千卡,脂肪和碳水化合物摄入量在正常范围内。尿白蛋白浓度和 MAU 与蛋白质、脂肪和热量摄入量有显著相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The association between urinary albumin excretion and nutrient status in patients with type 2 diabetes mellitus
Introduction: Diet plays an important role in blood glucose control and management of vascular complications in patients with type 2 diabetes mellitus (T2DM). Excess food intake can be a burden to kidney function and, therefore increase diabetic nephropathy in T2DM. Objectives: To determine the nutritional status and the association between nutrition regime and urinary albumin excretion in patients with T2DM in Vietnam. Patients and Methods: The study was carried out on 594 outpatients with T2DM at military hospital 103, Hanoi, Vietnam from December 2020 to April 2021. Nutrient regime was calculated based on the guidelines of Vietnam national institute of nutrition. Urinary albumin concentrations were measured by enzymatic turbidimeter autoanalyzer. Results: Twenty-four hours nutrient intake is as follows: mean total calorie intake of 1913.72 ± 235.87 kcal; protein of 80.76 ± 14.56 g, fat of 51.10 ± 13.97 g, carbohydrate of 284.83 ± 47.71 g, fiber of 7.35 g (5.85-8.87). Calorie, protein, fat, and carbohydrate intakes per kilogram of body weight (BW) are lower in men compared with women. In the univariate analysis, urinary albumin concentrations correlated with 24-hour protein intake (r = 0.391, P=0.02). In the univariate linear regression analysis, urinary albumin significantly correlated with protein intake (standardized B=0.616, P=0.004); fat intake (standardized B=0.601, P=0.002); diabetes duration (standardized B=0.441, P=0.028), and energy intake (standardized B=- 0.467, P=0.039). Microalbuminuria (MAU) significantly correlated with protein intake (OR=1.042, P=0.006) and HbA1c (OR = 1.664, P=0.013). Conclusion: In patients with T2DM in Vietnam, 24-hour calory intake is 1913.72 ± 235.87 kcal, fat and carbohydrate intakes are within the normal range. Urinary albumin concentrations and MAU had a significant correlation with protein, fat and calory intakes.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of Renal Injury Prevention
Journal of Renal Injury Prevention UROLOGY & NEPHROLOGY-
CiteScore
1.60
自引率
0.00%
发文量
36
期刊介绍: The Journal of Renal Injury Prevention (JRIP) is a quarterly peer-reviewed international journal devoted to the promotion of early diagnosis and prevention of renal diseases. It publishes in March, June, September and December of each year. It has pursued this aim through publishing editorials, original research articles, reviews, mini-reviews, commentaries, letters to the editor, hypothesis, case reports, epidemiology and prevention, news and views and renal biopsy teaching point. In this journal, particular emphasis is given to research, both experimental and clinical, aimed at protection/prevention of renal failure and modalities in the treatment of diabetic nephropathy. A further aim of this journal is to emphasize and strengthen the link between renal pathologists/nephropathologists and nephrologists. In addition, JRIP welcomes basic biomedical as well as pharmaceutical scientific research applied to clinical nephrology. Futuristic conceptual hypothesis that integrate various fields of acute kidney injury and renal tubular cell protection are encouraged to be submitted.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信