创办肾移植中心的初步经验:我们遇到的捐献者的非生物特征

Sonam Dargay, S. Bodapati, Sivaramakrishna Bodapati
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摘要

介绍:肾移植是治疗 ESRD 患者的最终方法。肾脏的捐献者可以是活体捐献者,也可以是遗体捐献者。活体捐献者是经过全面检查和筛选的健康人。为了另一个人的利益,我们让一个健康的人接受手术。因此,需要对捐肾者的健康状况进行评估:本研究是一项回顾性和前瞻性相结合的研究。回顾性数据来自一家大型三级医院泌尿科的肾移植患者病例表。对病例的前瞻性研究是通过跟踪捐献者的详细工作,包括病史、临床检查和与捐献者工作相关的检查,按照移植中心的方案进行的。对每个前瞻性病例都进行了供体肾切除术并发症的研究,并在供体肾切除术后进行了长达一年的随访。结果:在研究期间,共有 36 名供体接受了供体肾切除术。其中只有 2 例采用腹腔镜肾切除术,34 例采用标准腹膜后开放手术方法。13 名捐献者出现了术后并发症(36.11%)。住院时间为 5-35 天不等。大多数供体(44%)的住院时间在 10-15 天之间,其次是 5-10 天(30%-56%)。其余的住院时间从 2.78% 到 8.33% 不等。平均住院时间为 14.17 天,标准差为 6.45 天:结论:活体肾脏捐献具有诸多优点,仍然是治疗终末期肾病的最佳方案。由于血液透析带来的不便,以及血液透析的费用和患者劳动力的损失,使得肾移植成为无功能肾脏的最终替代方案。根据受者的病情选择移植时机的优势使肾移植远远优于尸体移植。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Initial Experiences in Starting a Renal Transplant Center: Ab-initio profile of donors we encountered
Introduction: Kidney transplantation is the ultimate treatment for people with ESRD. The Donors for such kidney can be either from living or from cadaver donors. The living donors are healthy people who are thoroughly worked up and screened. For the benefit of another person we subject a healthy subject to surgery. For this reason a study on how a donor’s health is affected as a result of kidney donation needs evaluation. Methods: This study is a combined retrospective and prospective study. The retrospective data were taken from the case sheet of patients maintained at the urology department of a large tertiary level hospital doing renal transplants. Prospective study of the cases were carried out by following up detail donor workup including history, clinical examination and investigations relevant to donor work up as per the protocol followed in the transplant center. Each prospective case were studied for complications of donor nephrectomy and followed up for a period of up to one year after donor nephrectomy.  Results: A total of 36 donors underwent donor nephrectomy during the study period. There were only two laparoscopic nephrectomies and 34 by standard retroperitoneal open surgical method. 13 donors had postoperative complications (36.11%). The duration of stay varied from 5-35 days. Majority of the donors (44%) had a stay within the range of 10-15 days, followed by a stay of 5-10 days (30-56 percent of the donors). The remaining stay ranged from 2.78% to 8.33 %. The average stay in the hospital was found to be 14.17 days with SD of 6.45 days. Conclusion: Living kidney donation with all its advantages still holds the best solution for end stage renal disease. The inconvenience of haemodialysis along with the cost and loss of labour of a patient on haemodialysis makes renal transplant the ultimate replacement of a non-functioning kidney. The advantage of timing of transplantion according to the condition of the recipient makes it far superior than cadaver grafts.
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