利用深度学习进行可靠的乳腺癌诊断:DCGAN 驱动的乳房 X 线照片合成与有效性评估

Dilawar Shah, Mohammad Asmat Ullah Khan, Mohammad Abrar
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引用次数: 0

摘要

乳腺癌成像对于快速检测和准确评估疾病至关重要。在建立能产生可靠结果的深度学习模型时,有注释的乳房 X 线照片数据的稀缺性是一个重大障碍。本文提出了一种新方法,利用深度卷积生成对抗网络(DCGAN)来有效解决数据可用性有限的问题。其主要目标是生成能准确再现真实数据中观察到的内在模式的合成乳腺图,从而增强当前数据集。所提出的合成方法得到了全面实验的支持,实验证明该方法能够准确再现乳房的各种视角。为了评估合成图像的可信度,并确定所获数据的临床意义,还进行了带有标准偏差的平均相似度评估。对每个类别内的一致性进行了全面评估,并测量了与每个类别平均值的偏差。使用指定阈值去除离群值是一个关键的过程要素。这一程序提高了每个图像聚类的准确度,并增强了合成数据集的总体可靠性。类聚类结果的可视化突出了生成图像与数据固有分布之间的一致性。剔除异常值后,可以观察到由同质数据点组成的独特而一致的聚类。拟议的相似性评估效果显著,消除了所有类别中的冗余和不相似图像。具体来说,在 600 张合成乳房照片中,正常类有 505 个实例,良性类有 495 个实例,恶性类有 490 个实例。为了进一步检验所提出模型的有效性,人类专家对合成图像进行了目测和验证。这凸显了我们的方法在识别大量异常值方面的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Reliable Breast Cancer Diagnosis with Deep Learning: DCGAN-Driven Mammogram Synthesis and Validity Assessment
Breast cancer imaging is paramount to quickly detecting and accurately evaluating the disease. The scarcity of annotated mammogram data presents a significant obstacle when building deep learning models that can produce reliable outcomes. This paper proposes a novel approach that utilizes deep convolutional generative adversarial networks (DCGANs) to effectively tackle the issue of limited data availability. The main goal is to produce synthetic mammograms that accurately reproduce the intrinsic patterns observed in real data, enhancing the current dataset. The proposed synthesis method is supported by thorough experimentation, demonstrating its ability to reproduce diverse viewpoints of the breast accurately. A mean similarity assessment with a standard deviation was performed to evaluate the credibility of the synthesized images and establish the clinical significance of the data obtained. A thorough evaluation of the uniformity within each class was conducted, and any deviations from each class’s mean values were measured. Including outlier removal using a specified threshold is a crucial process element. This procedure improves the accuracy level of each image cluster and strengthens the synthetic dataset’s general dependability. The visualization of the class clustering results highlights the alignment between the produced images and the inherent distribution of the data. After removing outliers, distinct and consistent clusters of homogeneous data points were observed. The proposed similarity assessment demonstrates noteworthy effectiveness, eliminating redundant and dissimilar images from all classes. Specifically, there are 505 instances in the normal class, 495 instances in the benign class, and 490 instances in the malignant class out of 600 synthetic mammograms for each class. To check the further validity of the proposed model, human experts visually inspected and validated synthetic images. This highlights the effectiveness of our methodology in identifying substantial outliers.
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