{"title":"一名格兰兹曼血栓性贫血患者反复突发感音神经性听力损失并伴有迷宫内出血:病例报告","authors":"Nobuyoshi Tsuzuki, K. Wasano, Hiroyuki Ozawa","doi":"10.3389/fauot.2024.1351382","DOIUrl":null,"url":null,"abstract":"Glanzmann thrombasthenia is a rare congenital bleeding disorder. Recent advances in magnetic resonance imaging (MRI) have made it possible to detect micro-lesions in the inner ear, such as intralabyrinthine hemorrhage, a rare disorder that causes sudden hearing loss or vertigo. We present a case of 62-year-old female with Glanzmann thrombasthenia. Over a 10-year period, the patient had experienced seven episodes of left-sided sudden hearing loss (SHL). Although each episode was treated with steroids, her left-ear hearing level gradually worsened. Head T1-weighted MRI performed 27 days after onset of the sixth SHL episode showed hyperintense lesions throughout the left inner ear. The patient was diagnosed with intralabyrinthine hemorrhage. When a patient with hematologic disease or who is on anticoagulant therapy presents with SHL or vertigo, T1-weighted MRI should be performed within 1 month of symptom onset to confirm intralabyrinthine hemorrhage.","PeriodicalId":483207,"journal":{"name":"Frontiers in Audiology and Otology","volume":"166 ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Repeated sudden sensorineural hearing loss with intralabyrinthine hemorrhage in a patient with Glanzmann thrombasthenia: case report\",\"authors\":\"Nobuyoshi Tsuzuki, K. Wasano, Hiroyuki Ozawa\",\"doi\":\"10.3389/fauot.2024.1351382\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Glanzmann thrombasthenia is a rare congenital bleeding disorder. Recent advances in magnetic resonance imaging (MRI) have made it possible to detect micro-lesions in the inner ear, such as intralabyrinthine hemorrhage, a rare disorder that causes sudden hearing loss or vertigo. We present a case of 62-year-old female with Glanzmann thrombasthenia. Over a 10-year period, the patient had experienced seven episodes of left-sided sudden hearing loss (SHL). Although each episode was treated with steroids, her left-ear hearing level gradually worsened. Head T1-weighted MRI performed 27 days after onset of the sixth SHL episode showed hyperintense lesions throughout the left inner ear. The patient was diagnosed with intralabyrinthine hemorrhage. When a patient with hematologic disease or who is on anticoagulant therapy presents with SHL or vertigo, T1-weighted MRI should be performed within 1 month of symptom onset to confirm intralabyrinthine hemorrhage.\",\"PeriodicalId\":483207,\"journal\":{\"name\":\"Frontiers in Audiology and Otology\",\"volume\":\"166 \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in Audiology and Otology\",\"FirstCategoryId\":\"0\",\"ListUrlMain\":\"https://doi.org/10.3389/fauot.2024.1351382\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Audiology and Otology","FirstCategoryId":"0","ListUrlMain":"https://doi.org/10.3389/fauot.2024.1351382","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Repeated sudden sensorineural hearing loss with intralabyrinthine hemorrhage in a patient with Glanzmann thrombasthenia: case report
Glanzmann thrombasthenia is a rare congenital bleeding disorder. Recent advances in magnetic resonance imaging (MRI) have made it possible to detect micro-lesions in the inner ear, such as intralabyrinthine hemorrhage, a rare disorder that causes sudden hearing loss or vertigo. We present a case of 62-year-old female with Glanzmann thrombasthenia. Over a 10-year period, the patient had experienced seven episodes of left-sided sudden hearing loss (SHL). Although each episode was treated with steroids, her left-ear hearing level gradually worsened. Head T1-weighted MRI performed 27 days after onset of the sixth SHL episode showed hyperintense lesions throughout the left inner ear. The patient was diagnosed with intralabyrinthine hemorrhage. When a patient with hematologic disease or who is on anticoagulant therapy presents with SHL or vertigo, T1-weighted MRI should be performed within 1 month of symptom onset to confirm intralabyrinthine hemorrhage.