一种 Siddha 多草药配方 Vaividanga Choornam 的药理、理化、植物化学和色谱表征

Q3 Pharmacology, Toxicology and Pharmaceutics
P. Parvathy, M. Natarajan, B. Kannan, G. Lekha, A. Kanagarajan
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引用次数: 0

摘要

根据活性成分的浓度确定草药配方的标准化对于评价药物质量至关重要。目前的研究旨在调查 Vaividanga Choornam(一种传统的释迦多草药成分)的植物化学和物理化学分析。这种 Vaividanga Choornam 含有 Vaividangam(Embelica ribesBurm.)、Milagu(Piper nigrumL.)、Chukku(Zingiber officinale Rosc.)、Omam(Trachyspermum ammi (L) Sprague)和 Nilavaagai leaves(Cassia angustifolia Vahl.)它可治疗痰病、便秘、消化不良、胃肠胀气、灼热感、支气管哮喘和卡帕病。此外,它还是治疗幼儿因蠕虫负担过重而引起的肠道蠕虫病的有效药物。本研究旨在通过药理研究、初步植物化学分析、理化指标(如灰分值、萃取值和干燥失重),并借助高效薄层色谱法(HPTLC)、傅立叶变换红外光谱仪和紫外可见光谱分析来评估 Vaividanga Choornam 的质量。分析结果表明,该药物含有多种植物化学物质。结果表明,该药物质量合格,可用于制定药物的药典标准。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pharmacognostic, Physicochemical, Phytochemical and Chromatographic Characterization of Vaividanga Choornam, A Siddha Polyherbal Formulation
Standardization of herbal formulations as determined by the concentration of their activecomponents is essential to appraise the quality of drugs. The current study intends to investigate the phytochemical and physicochemical analyses of Vaividanga Choornam, a traditional Siddha polyherbal composition. This Vaividanga choornam contains the ingredients like Vaividangam (Embelica ribesBurm.), Milagu (Piper nigrumL.), Chukku (Zingiber officinale Rosc.), Omam (Trachyspermum ammi (L) Sprague), and Nilavaagai leaves (Cassia angustifolia Vahl. - syn. Cassia senna). It treatspitha diseases, constipation, indigestion, flatulence, burning sensation, bronchial asthma, and Kapha diseases. It is also an effective medicine for treating intestinal helminths caused by heavy worm burdens in young children. This study aims to estimate the quality of Vaividanga Choornam by performing pharmacognostic studies, preliminary phytochemical analysis, physiochemical parameters like ash value, extractive value, and loss on drying as per pharmacopoeial laboratory for Indian medicine guidelines, and also with the help of tests done with High-Performance Thin Layer Chromatography (HPTLC), FTIR Spectroscopy, and UV -Vis spectrometric analyses. The results obtained fromthose analyses showed the presence of various phytochemicals. The results indicate that the drug is of adequate quality and may be used to establish pharmacopeial standards of the medicine.
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来源期刊
Research Journal of Pharmacy and Technology
Research Journal of Pharmacy and Technology Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
CiteScore
1.40
自引率
0.00%
发文量
0
期刊介绍: Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.
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