器官和组织的辐射损伤:发生机制、预防和治疗方法:综述

Q4 Medicine
Daiana A. Balaeva, D. Romanov, O. Trofimova, Zarina Z. Gadzhibabaeva, Y. Y. Gorchak, Garia A. Gariaev
{"title":"器官和组织的辐射损伤:发生机制、预防和治疗方法:综述","authors":"Daiana A. Balaeva, D. Romanov, O. Trofimova, Zarina Z. Gadzhibabaeva, Y. Y. Gorchak, Garia A. Gariaev","doi":"10.26442/18151434.2023.4.202572","DOIUrl":null,"url":null,"abstract":"In modern medicine, radiation therapy (RT) is one of the main therapies for cancer. According to the World Health Organization, about 70% of patients diagnosed with cancer require RT at some stage of treatment. Development and improvement of methods for early diagnosis of cancers, multimodal therapy for cancer patients, including surgical intervention, new drug treatment regimens, modern methods of conformal 3D-RT and proton therapy significantly improved the treatment outcomes of patients and increased their life expectancy. Modern RT is a high-tech chain of sequential use of complex technical devices and mathematical calculations to destroy the tumor without adversely affecting the surrounding normal tissues. Some patients develop radiation injuries to normal organs and tissues that reduce their quality of life. Prevention and treatment of such injuries are urgent problems of modern oncology. The article addresses the pathogenesis and mechanism of the development of systemic and local radiation responses, as well as methods of treatment and prevention of some of them. Three electronic databases, including PubMed, Cochrane and EMBASE, and Russian radiotherapists' publications, were used for systematic review in the information retrieval process.","PeriodicalId":16401,"journal":{"name":"Journal of Modern Oncology","volume":"109 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Radiation injuries of organs and tissues: mechanisms of occurrence, methods of prevention and treatment: A review\",\"authors\":\"Daiana A. Balaeva, D. Romanov, O. Trofimova, Zarina Z. Gadzhibabaeva, Y. Y. Gorchak, Garia A. Gariaev\",\"doi\":\"10.26442/18151434.2023.4.202572\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In modern medicine, radiation therapy (RT) is one of the main therapies for cancer. According to the World Health Organization, about 70% of patients diagnosed with cancer require RT at some stage of treatment. Development and improvement of methods for early diagnosis of cancers, multimodal therapy for cancer patients, including surgical intervention, new drug treatment regimens, modern methods of conformal 3D-RT and proton therapy significantly improved the treatment outcomes of patients and increased their life expectancy. Modern RT is a high-tech chain of sequential use of complex technical devices and mathematical calculations to destroy the tumor without adversely affecting the surrounding normal tissues. Some patients develop radiation injuries to normal organs and tissues that reduce their quality of life. Prevention and treatment of such injuries are urgent problems of modern oncology. The article addresses the pathogenesis and mechanism of the development of systemic and local radiation responses, as well as methods of treatment and prevention of some of them. Three electronic databases, including PubMed, Cochrane and EMBASE, and Russian radiotherapists' publications, were used for systematic review in the information retrieval process.\",\"PeriodicalId\":16401,\"journal\":{\"name\":\"Journal of Modern Oncology\",\"volume\":\"109 2\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Modern Oncology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.26442/18151434.2023.4.202572\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Modern Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.26442/18151434.2023.4.202572","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

在现代医学中,放射治疗(RT)是癌症的主要疗法之一。据世界卫生组织统计,约 70% 的确诊癌症患者在治疗的某个阶段需要接受 RT 治疗。癌症早期诊断方法的发展和改进、癌症患者的多模式治疗(包括外科干预)、新的药物治疗方案、现代适形三维放射治疗方法和质子治疗方法大大改善了患者的治疗效果,延长了患者的预期寿命。现代 RT 是一个高科技链条,依次使用复杂的技术设备和数学计算来摧毁肿瘤,同时不会对周围正常组织造成不利影响。一些患者的正常器官和组织会受到辐射损伤,从而降低其生活质量。预防和治疗此类损伤是现代肿瘤学亟待解决的问题。文章探讨了全身和局部辐射反应的发病机理和机制,以及一些辐射反应的治疗和预防方法。在信息检索过程中,使用了三个电子数据库(包括 PubMed、Cochrane 和 EMBASE)以及俄罗斯放射治疗专家的出版物进行系统性审查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Radiation injuries of organs and tissues: mechanisms of occurrence, methods of prevention and treatment: A review
In modern medicine, radiation therapy (RT) is one of the main therapies for cancer. According to the World Health Organization, about 70% of patients diagnosed with cancer require RT at some stage of treatment. Development and improvement of methods for early diagnosis of cancers, multimodal therapy for cancer patients, including surgical intervention, new drug treatment regimens, modern methods of conformal 3D-RT and proton therapy significantly improved the treatment outcomes of patients and increased their life expectancy. Modern RT is a high-tech chain of sequential use of complex technical devices and mathematical calculations to destroy the tumor without adversely affecting the surrounding normal tissues. Some patients develop radiation injuries to normal organs and tissues that reduce their quality of life. Prevention and treatment of such injuries are urgent problems of modern oncology. The article addresses the pathogenesis and mechanism of the development of systemic and local radiation responses, as well as methods of treatment and prevention of some of them. Three electronic databases, including PubMed, Cochrane and EMBASE, and Russian radiotherapists' publications, were used for systematic review in the information retrieval process.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of Modern Oncology
Journal of Modern Oncology Medicine-Oncology
CiteScore
0.50
自引率
0.00%
发文量
0
审稿时长
5 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信