sFlt1/PIGF比率可预测早期胎儿生长受限的胎儿恶化速度：历史队列研究

Obstetric Anesthesia Digest Pub Date : 2024-02-22 DOI:10.1097/01.aoa.0001005404.00620.ec

C.R. Palma Dos Reis, S. Brás, T. Meneses, A.S. Cerdeira, M. Vatish, A.T. Martins

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摘要

(Acta Obstet Gynecol Scand. 2023;102:635-643) 据预测，胎盘生长因子（PlGF）和酪氨酸激酶1（sFlt1）都是导致胎盘功能受损的因素，而胎盘功能受损已知会导致子痫前期和胎儿生长受限（FGR）等疾病。先前的研究显示，这些疾病患者体内的 PlGF 和 sFlt1 水平存在波动。本研究旨在确定高水平的 PlGF 和 sFlt1 对新生儿 FGR 恶化的影响。

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The sFlt1/PIGF Ratio Predicts Faster Fetal Deterioration in Early Fetal Growth Restriction: A Historical Cohort Study

(Acta Obstet Gynecol Scand. 2023;102:635–643) Both placental growth factor (PlGF) and tyrosine kinase 1 (sFlt1) are predicted to be factors in impaired placentation, which is known to lead to diseases such as pre-eclampsia and fetal growth restriction (FGR). Previous studies have shown fluctuations in the levels of PlGF and sFlt1 in patients with these diseases. This study aimed to determine the effects that high levels of PlGF and sFlt1 have on the deterioration of FGR in neonates.

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Obstetric Anesthesia Digest

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