追寻生化巨匠的足迹:雅库布-帕尔纳斯的科学遗产

L. Kobylinska
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引用次数: 0

摘要

本文旨在纪念生物化学领域的杰出人物、利沃夫医科大学生理(生物)化学系教授雅库布-卡罗尔-帕尔纳斯。文章强调了雅库布-帕尔纳斯对乌克兰生物化学的深远影响,揭示了他在利沃夫大学工作的二十年间高产的人格魅力。他的研究为揭示无氧葡萄糖代谢做出了重大贡献,后来被公认为恩伯登-迈耶霍夫-帕尔纳斯途径。雅库布-帕尔纳斯教授和他的利沃夫学派对与无氧肌肉功能和酒精发酵相关的酶转化、糖原磷解、糖酵解中的 ATP 合成的启示、在生物实验中率先使用放射性标记磷等方面进行了关键性研究。关键词生物化学、恩布登-迈耶霍夫-帕尔纳斯途径、雅各布-帕尔纳斯、利沃夫
本文章由计算机程序翻译,如有差异,请以英文原文为准。
In the footsteps of a biochemical luminary: the scientific legacy of Yakub Parnas
The article is dedicated to commemorating Yakub Karol Parnas, an eminent figure in biochemistry and a professor in the Department of Physiological (Biological) Chemistry at Lviv Medical University. It underscores the profound impact of Yakub Parnas on Ukrainian biochemistry, shedding light on intriguing facets­ of his personality during his highly productive two decades at Lviv University. His research significantly contributed to the unveiling of anaerobic glucose metabolism, later acknowledged as the Embden-Meyerhoff-Parnas pathway. Professor Yakub Parnas and his Lviv school conducted pivotal studies on enzymatic transformations associated with anaerobic muscle function and alcoholic fermentation, glycogen phosphorolysis, revelation of ATP synthesis within glycolysis, pioneering use of radioactively labeled phosphorus in biological experiments. Keywords: Biochemistry, Embden-Meyerhoff-Parnas pathway, Jakub Parnas, Lviv
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