Vishav Yadav, Sanjeev Bhagat, Khushboo Goel, R. Sibia, D. Sharma, T. Sidhu, Saivi Rajdev, Ankita Aggarwal
{"title":"印度与 COVID-19 相关的粘孢子菌病疫情的结果:为期两年的前瞻性跟踪研究","authors":"Vishav Yadav, Sanjeev Bhagat, Khushboo Goel, R. Sibia, D. Sharma, T. Sidhu, Saivi Rajdev, Ankita Aggarwal","doi":"10.1002/wjo2.162","DOIUrl":null,"url":null,"abstract":"The objective of this study was to study the various outcomes among coronavirus disease 2019 (COVID‐19)‐associated mucormycosis (CAM) in terms of morbidity and mortality.A prospective study was done on 107 patients (60 male, 47 female) in the Department of Otolaryngology and Head and Neck Surgery, Government Medical College, Patiala, India, diagnosed with CAM from April 2021 to August 2021. The patients were managed both medically and surgically. The follow‐up was done up to 2 years to assess the various outcomes.Out of 107 patients, short‐term (3 months) survival was 68.22%, and long‐term (2 years) survival was 52.34%. Overall mortality was 47.66%, with short‐term mortality of 31.77% and long‐term mortality of 15.89%. Eye loss was seen in 17 patients, residual ophthalmoplegia in 12, palatal loss in 15, depression in 56, cerebrospinal fluid rhinorrhea in two, and recurrence in two patients.In conclusion, despite early management and successful initial outcome, the patients are still haunted by the after‐effects of CAM like residual morbidity in terms of eye and palate loss, ophthalmoplegia, and depression. Delayed mortality has also been noticed over 2 years of follow‐up.","PeriodicalId":510563,"journal":{"name":"World Journal of Otorhinolaryngology - Head and Neck Surgery","volume":"68 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Outcomes of COVID‐19‐associated mucormycosis epidemic in India: A prospective 2‐year follow‐up study\",\"authors\":\"Vishav Yadav, Sanjeev Bhagat, Khushboo Goel, R. Sibia, D. Sharma, T. Sidhu, Saivi Rajdev, Ankita Aggarwal\",\"doi\":\"10.1002/wjo2.162\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The objective of this study was to study the various outcomes among coronavirus disease 2019 (COVID‐19)‐associated mucormycosis (CAM) in terms of morbidity and mortality.A prospective study was done on 107 patients (60 male, 47 female) in the Department of Otolaryngology and Head and Neck Surgery, Government Medical College, Patiala, India, diagnosed with CAM from April 2021 to August 2021. The patients were managed both medically and surgically. The follow‐up was done up to 2 years to assess the various outcomes.Out of 107 patients, short‐term (3 months) survival was 68.22%, and long‐term (2 years) survival was 52.34%. Overall mortality was 47.66%, with short‐term mortality of 31.77% and long‐term mortality of 15.89%. Eye loss was seen in 17 patients, residual ophthalmoplegia in 12, palatal loss in 15, depression in 56, cerebrospinal fluid rhinorrhea in two, and recurrence in two patients.In conclusion, despite early management and successful initial outcome, the patients are still haunted by the after‐effects of CAM like residual morbidity in terms of eye and palate loss, ophthalmoplegia, and depression. Delayed mortality has also been noticed over 2 years of follow‐up.\",\"PeriodicalId\":510563,\"journal\":{\"name\":\"World Journal of Otorhinolaryngology - Head and Neck Surgery\",\"volume\":\"68 2\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World Journal of Otorhinolaryngology - Head and Neck Surgery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/wjo2.162\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Otorhinolaryngology - Head and Neck Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/wjo2.162","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Outcomes of COVID‐19‐associated mucormycosis epidemic in India: A prospective 2‐year follow‐up study
The objective of this study was to study the various outcomes among coronavirus disease 2019 (COVID‐19)‐associated mucormycosis (CAM) in terms of morbidity and mortality.A prospective study was done on 107 patients (60 male, 47 female) in the Department of Otolaryngology and Head and Neck Surgery, Government Medical College, Patiala, India, diagnosed with CAM from April 2021 to August 2021. The patients were managed both medically and surgically. The follow‐up was done up to 2 years to assess the various outcomes.Out of 107 patients, short‐term (3 months) survival was 68.22%, and long‐term (2 years) survival was 52.34%. Overall mortality was 47.66%, with short‐term mortality of 31.77% and long‐term mortality of 15.89%. Eye loss was seen in 17 patients, residual ophthalmoplegia in 12, palatal loss in 15, depression in 56, cerebrospinal fluid rhinorrhea in two, and recurrence in two patients.In conclusion, despite early management and successful initial outcome, the patients are still haunted by the after‐effects of CAM like residual morbidity in terms of eye and palate loss, ophthalmoplegia, and depression. Delayed mortality has also been noticed over 2 years of follow‐up.