通过抑制炎症细胞因子抑制皮质醇分泌来增强健康成人志愿者的代谢功能

Rotu Arientare Rume, Oyovwi Mega Obukohwo, Peggy Ejiro Ohwin, Oyelere Abosede Oreoluwa
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摘要

事实证明,经常参加体育锻炼可以改善新陈代谢,延缓衰老,降低患肥胖症、2 型糖尿病和心血管疾病等各种健康问题的可能性。因此,我们评估了跳舞对健康成年人心血管、肝酶和生化指标的影响。研究选择了 40 名健康成年人(20-40 岁),并计算了他们的平均年龄。有某些健康状况或习惯的人不得参加。研究选择了二十(20)名男性和二十(20)名女性,研究内容包括每天跳舞 15 分钟,每周五天,持续四周。研究人员比较了跳舞前和跳舞后两组的变化。结果显示,跳舞对健康和幸福有积极影响。在为期四周的舞蹈干预中,对两组进行了比较,以分析心血管、肝酶和血脂概况的变化。两组人员在课程前后都接受了评估,0 周时进行首次评估,4 周时进行后续评估。这项研究发现,为期 4 周的舞蹈锻炼改善了男女两性的心血管和血脂状况(P < 0.05)。这些有利影响体现在收缩压和舒张压降低、总胆固醇和甘油三酯降低、低密度脂蛋白降低以及高密度脂蛋白相应增加。这项研究发现,与运动前的水平相比,参加量身定制的舞蹈锻炼计划可降低血糖、胰岛素和 HOMA 指数水平。此外,谷丙转氨酶(ALT)、谷草转氨酶(AST)和谷草转氨酶(GGT)的水平也大幅下降,而谷草转氨酶(ALP)和低密度脂蛋白胆固醇(LDH)也有所下降。舞蹈后运动 24 小时后,肾功能(包括转氨酶、肌酐和尿酸)也有所下降。在健康成年人中,舞蹈运动后 24 小时可降低血清 IL-6、CRP 和应激激素(肾上腺素和皮质醇)水平,并提高 IL-10 水平(P < 0.05)。可以证明,舞蹈是一种实用的非药物方法,有助于预防代谢综合征,并通过增加健康成年人的皮质醇分泌来减少炎症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dancing Exercise Enhances Metabolic Functions via Hypercortisolism-Mediated Inhibition of Inflammatory Cytokines in Healthy Adult Volunteers
Regular physical activity has been proven to improve metabolism, slow aging, and decrease the likelihood of various health conditions such as obesity, type 2 diabetes, and cardiovascular disorders. Hence, dancing was evaluated for its effects on cardiovascular, liver enzymes, and biochemical markers among healthy adults. Forty (40) healthy adults (20-40 years old) were chosen for the study, with an average age calculated. Those with certain health conditions or habits were not allowed to participate. Twenty (20) men and 20 women were chosen for the study, which involved dancing for 15 minutes a day, five days a week, for four weeks. Pre- and post-dancing groups were compared to measure any changes. Results indicated positive effects on health and well-being. The two groups were compared to analyze changes to cardiovascular, liver enzymes, and lipid profiles over a 4-week dance intervention. Both groups received assessments before and after the program, with the initial assessment taking place at 0 weeks and a follow-up at 4 weeks. This study found that a 4-week period of dancing exercise improved cardiovascular and lipid profiles (p < 0.05) in both genders. These favorable impacts were reflected in lower systolic and diastolic blood pressure, decreased total cholesterol and triglycerides, and lowered LDL with corresponding increases in HDL. This study found that participating in a tailored dance exercise program decreased glucose, insulin, and HOMA index levels compared to pre-exercise levels. Additionally, levels of ALT, AST, and GGT dropped considerably, while ALP and LDH also decreased. Kidney function, including aminotransferase, creatinine, and uric acid, was also reduced after 24 hours of post-dancing exercise. Twenty-four hours of Post-dancing exercise was found to decrease serum IL-6, CRP, and stress hormones (epinephrine and cortisol) levels as well as increased IL-10 levels in healthy adults (P < 0.05). Dancing could be demonstrated to be a practical non-medicinal approach to help prevent metabolic syndrome and reduce inflammation through increased cortisol production in healthy adults.
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