抗磷脂综合征和系统性红斑狼疮的避孕措施(根据欧洲风湿病学协会联盟/美国风湿病学会(EULAR/ACR)的建议

T. Reshetnyak, S. B. Kertchelaeva, N. Kosheleva
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引用次数: 0

摘要

维护和加强人口健康是社会的主要职能之一。如果医学界和社会对避孕的重要性认识不足,就会导致人口的生殖健康受到损害。有效、安全的避孕方法的基本知识对每一位风湿病医生来说都很重要,因为生殖健康既影响患者的一般状况,也影响主要风湿病(RH)的病程。这对于抗磷脂抗体(aPL)阳性、抗磷脂综合征(APS)和系统性红斑狼疮(SLE)患者来说尤其如此。抗磷脂抗体/抗磷脂综合征的存在以及系统性红斑狼疮的活动性是决定 RH 患者避孕方法选择和激素避孕风险的主要因素。同时,在这类患者中使用适当的(高效、安全的)避孕疗法不仅可以计划生育,还可以避免在疾病活动、使用胚胎毒性药物和致畸药物的情况下意外怀孕,以及对并发病症进行最佳治疗。本刊物专门讨论最 "脆弱 "的一类风湿病患者--aPL、APS 和系统性红斑狼疮阳性患者--的主要避孕问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Contraception for antiphospholipid syndrome and systemic lupus erythematosus (according to the recommendations of the European Alliance of Associations for Rheumatology/American College of Rheumatology, EULAR/ACR)
Maintaining and strengthening the health of the population is one of the primary functions of society. Inadequate understanding of the importance of contraception by the medical community and its application by society can lead to the population’s reproductive health becoming compromised. Basic knowledge of effective and safe contraceptive methods is important for every rheumatologist, as reproductive health affects both the general condition of patients and the course of the main rheumatic diseases (RH). This is particularly true for patients with antiphospholipid antibody (aPL) positivity, antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). The presence of aPL/APS, as well as the activity of SLE, are the main factors determining the choice of contraceptive method and the risk of hormonal contraception in patients with RH. Meanwhile, the use of appropriate (highly effective and safe) contraceptive therapy in this category of patients allows not only to plan the birth of a child, but also to avoid unwanted pregnancy in cases of disease activity, the use of embryotoxic and teratogenic drugs, as well as to carry out optimal treatment of concomitant pathology, which the supervising rheumatologist should be well aware of. This publication is devoted to the consideration of the main issues of contraception in the most “vulnerable” category of patients with RH – with positive aPL, APS and SLE.
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