{"title":"儿童超重和肥胖是青春期提前的预测因素：元分析","authors":"O. P. Kovtun, T. Brodovskaya, M. A. Ustyuzhanina","doi":"10.15690/vramn8810","DOIUrl":null,"url":null,"abstract":"Background. Obesity and overweight among children remains to be an actual problem. To date, the relationship between them and puberty has not been determined. Objective — to estimate the overweight and obesity impact on puberty in boys and girls. \nMethods. The search for relevant sources was carried out in the Medline/PubMed, Researchgate, Elibrary, www.clinicaltrials.gov, www.clinicaltrialresults.org databases for the period from 2000 to 2023. Nine studies with a total of 24, 542 participants aged 0 to 18 years were selected for inclusion in the meta-analysis. \nResults. A significant relationship was established between precocious puberty in overweight/obese girls OR 2.23 (CI 1.63–3.05; p 0.00001) and a tendency to accelerated puberty in boys OR 1.43 (CI 0.92–2.23; p = 0.11). \nConclusion. Overweight and obesity in children are determinants of faster rates of puberty, in particular among girls.","PeriodicalId":178392,"journal":{"name":"Annals of the Russian academy of medical sciences","volume":"25 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Overweight and Obesity in Children as Predictors of Early Puberty: A Meta-Analysis\",\"authors\":\"O. P. Kovtun, T. Brodovskaya, M. A. Ustyuzhanina\",\"doi\":\"10.15690/vramn8810\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background. Obesity and overweight among children remains to be an actual problem. To date, the relationship between them and puberty has not been determined. Objective — to estimate the overweight and obesity impact on puberty in boys and girls. \\nMethods. The search for relevant sources was carried out in the Medline/PubMed, Researchgate, Elibrary, www.clinicaltrials.gov, www.clinicaltrialresults.org databases for the period from 2000 to 2023. Nine studies with a total of 24, 542 participants aged 0 to 18 years were selected for inclusion in the meta-analysis. \\nResults. A significant relationship was established between precocious puberty in overweight/obese girls OR 2.23 (CI 1.63–3.05; p 0.00001) and a tendency to accelerated puberty in boys OR 1.43 (CI 0.92–2.23; p = 0.11). \\nConclusion. Overweight and obesity in children are determinants of faster rates of puberty, in particular among girls.\",\"PeriodicalId\":178392,\"journal\":{\"name\":\"Annals of the Russian academy of medical sciences\",\"volume\":\"25 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of the Russian academy of medical sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15690/vramn8810\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of the Russian academy of medical sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15690/vramn8810","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Overweight and Obesity in Children as Predictors of Early Puberty: A Meta-Analysis
Background. Obesity and overweight among children remains to be an actual problem. To date, the relationship between them and puberty has not been determined. Objective — to estimate the overweight and obesity impact on puberty in boys and girls.
Methods. The search for relevant sources was carried out in the Medline/PubMed, Researchgate, Elibrary, www.clinicaltrials.gov, www.clinicaltrialresults.org databases for the period from 2000 to 2023. Nine studies with a total of 24, 542 participants aged 0 to 18 years were selected for inclusion in the meta-analysis.
Results. A significant relationship was established between precocious puberty in overweight/obese girls OR 2.23 (CI 1.63–3.05; p 0.00001) and a tendency to accelerated puberty in boys OR 1.43 (CI 0.92–2.23; p = 0.11).
Conclusion. Overweight and obesity in children are determinants of faster rates of puberty, in particular among girls.
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