基于磁共振的骨骼三维模型可为 SCFE 患者提供无辐射的术前患者特异性分析和三维打印技术

Till D Lerch, Tilman Kaim, Valentin Grob, M. Hanke, Florian Schmaranzer, S. D. Steppacher, Jasmin D. Busch, Kai Ziebarth
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摘要

目的:股骨头骺滑脱(SCFE)是一种常见的小儿髋关节疾病,具有骨关节炎和撞击畸形的风险。因此,我们研究了磁共振成像(MRI)骨骼分割和三维打印的可行性,以及使用基于 MRI 的三维模型进行三维 ROM 模拟的可行性。研究方法进行了一项回顾性研究,涉及 22 名有症状的 SCFE 患者(22 个髋关节)。所有患者术前均接受了髋关节磁共振检查,并获得了骨盆冠状位高分辨率图像(T1 图像)。切片厚度为 0.8-1.2 毫米。平均年龄为(12 ± 2)岁(59%为男性患者)。所有患者均接受了手术治疗。进行了基于核磁共振成像的半自动骨骼分割,并进行了手动修正和三维打印塑料三维模型。对虚拟三维模型进行了测试,以便利用膝关节图像对患者进行计算机辅助三维 ROM 模拟,并与单侧 SCFE 的无症状对侧髋关节(15 个髋关节,对照组)进行比较。结果:基于磁共振成像的骨分割是可行的(所有患者,100%,4.5 小时,平均 272 ± 52 分钟)。塑料三维模型的三维打印是可行的(所有患者,100%),治疗外科医生认为这有助于对重度和中度 SCFE 进行畸形分析。三维ROM模拟显示,与对照组(122 ± 9°和36 ± 11°)相比,重度SCFE患者的MRI显示屈曲(48 ± 40°)和屈曲90°的IR(-14 ± 21°,IRF-90°)明显减少(p < 0.001)。滑动角度从术前的 54 ± 15° 显著改善到术后的 4 ± 2°(p < 0.001)。结论:基于 MRI 的三维模型对 SCFE 患者是可行的。三维模型可用于严重SCFE患者的术前三维打印、畸形分析和ROM模拟。这有助于针对患者的诊断、治疗决策和术前规划。基于核磁共振成像的三维模型无辐射,将来可取代基于 CT 的三维模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
MR-based Bony 3D models enable radiation-free preoperative patient-specific analysis and 3D printing for SCFE patients
Objectives: Slipped capital femoral epiphyses (SCFE) is a common pediatric hip disease with the risk of osteoarthritis and impingement deformities, and 3D models could be useful for patient-specific analysis. Therefore, magnetic resonance imaging (MRI) bone segmentation and feasibility of 3D printing and of 3D ROM simulation using MRI-based 3D models were investigated. Methods: A retrospective study involving 22 symptomatic patients (22 hips) with SCFE was performed. All patients underwent preoperative hip MR with pelvic coronal high-resolution images (T1 images). Slice thickness was 0.8–1.2 mm. Mean age was 12 ± 2 years (59% male patients). All patients underwent surgical treatment. Semi-automatic MRI-based bone segmentation with manual corrections and 3D printing of plastic 3D models was performed. Virtual 3D models were tested for computer-assisted 3D ROM simulation of patients with knee images and were compared to asymptomatic contralateral hips with unilateral SCFE (15 hips, control group). Results: MRI-based bone segmentation was feasible (all patients, 100%, in 4.5 h, mean 272 ± 52 min). Three-dimensional printing of plastic 3D models was feasible (all patients, 100%) and was considered helpful for deformity analysis by the treating surgeons for severe and moderate SCFE. Three-dimensional ROM simulation showed significantly (p < 0.001) decreased flexion (48 ± 40°) and IR in 90° of flexion (–14 ± 21°, IRF-90°) for severe SCFE patients with MRI compared to control group (122 ± 9° and 36 ± 11°). Slip angle improved significantly (p < 0.001) from preoperative 54 ± 15° to postoperative 4 ± 2°. Conclusion: MRI-based 3D models were feasible for SCFE patients. Three-dimensional models could be useful for severe SCFE patients for preoperative 3D printing and deformity analysis and for ROM simulation. This could aid for patient-specific diagnosis, treatment decisions, and preoperative planning. MRI-based 3D models are radiation-free and could be used instead of CT-based 3D models in the future.
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