非糖尿病患者在不同麻醉技术(全身麻醉和脊柱麻醉)下的术后血糖水平

Md. Monzorull Islam, Md. Sirajul Islam, Salim Al Mamun, Sultana Jahan Hema, Rowshon Ara Ahmed
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摘要

导言:过去几十年来,人们一直在广泛评估和讨论麻醉剂和手术引起的新陈代谢和荷尔蒙反应。在正常人体内,合成代谢和分解代谢是微妙平衡的。手术会产生应激反应,导致各种生化和激素变化。除手术应激反应外,气管插管、麻醉恢复和术后疼痛等麻醉相关程序也会增加应激反应引起的激素变化。本研究旨在了解非糖尿病患者在各种麻醉技术(全身麻醉和脊柱麻醉)下的术后血糖水平。研究方法2022 年 1 月至 12 月,在孟加拉国达卡市安维尔汗现代医学院医院麻醉科对接受手术的患者进行了一项基于机构的横断面观察研究。共有 120 名非糖尿病患者接受了全身或脊髓麻醉手术。数据使用 SPSS 20.0 视窗版本进行分析。采用卡方检验(Chi-Square test)显示分类变量之间的关联,采用独立样本t检验(Independent sample t test)显示正态分布连续变量之间的均值差异。所有统计检验均为双尾检验,P 值小于 0.05 为显著。结果65.8%的研究对象接受了全身麻醉,34.2%接受了脊髓麻醉。术后,41.6%的研究对象血糖在糖尿病前期范围内,20.0%的研究对象血糖在糖尿病范围内。术后高血糖(IFG + 糖尿病)发生率为 61.7%。在接受全身麻醉的研究人群中,术后血浆葡萄糖平均值明显较高。年龄增长、女性性别、超重、肥胖、高血压和甲状腺功能减退症与术后高血糖的高风险明显相关。结论术后高血糖的发生率很高。发生频率
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Post-Operative Blood Glucose Level in Various Anaesthetic Techniques (General & Spinal) Among Non-Diabetics Patients
Introduction: The metabolic and hormonal responses to anaesthetics and surgery have been a subject of extensive evaluation and discussion for the past many decades. In normal man, anabolism and catabolism are finely balanced. Surgery produces a stress response resulting in various biochemical and hormonal changes. Apart from surgical stress, anesthesia related procedures like Tracheal intubation, recovery from anesthesia, and post-operative pain can increase the stress induced hormonal changes. This study aims to find out post-operative blood glucose level in various anaesthetic techniques (general & spinal) among non-diabetics patients. Methods: An institution based, observational, cross-sectional study was conducted among patients who were operated at Dept. of Anesthesiology, Anwer Khan Modern Medical College Hospital, Dhaka, Bangladesh from January to December 2022. A total of 120 non diabetes patients who received either general or spinal anesthesia for their surgery. Data was analyzed using SPSS, version 20.0 for windows. Chi-Square test was used to show association between categorical variables and independent sample t-test was used to show mean difference among normally distributed continuous variables. All statistical tests were 2-tailed and a p-value of <0.05 was considered significant. Results: 65.8% of study population received general anesthesia and 34.2% received spinal anesthesia. In postoperative period, 41.6% of study population had their plasma glucose in pre diabetes range and 20.0% had their plasma glucose in diabetes range. Frequency of postoperative hyperglycemia (IFG + Diabetes) was 61.7%. Mean postoperative plasma glucose was significantly higher among study population who received general anesthesia. Increasing age, female gender, overweight, obesity, hypertension and hypothyroidism was significantly associated with high risk of postoperative hyperglycemia. Conclusion: There is high prevalence of postoperative hyperglycemia. The frequency of
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