Novel gastrointestinal procedures

Technological advancements have shaped the landscape of modern gastroenterology thanks to the accessibility of the gastrointestinal tract to endoscopic interventions. Over the last decade increasing research efforts have been dedicated to integrating artificial intelligence into endoscopy to allow the early detection of premalignant and early malignant lesions. Meanwhile, progress has been made in minimally invasive cell collection devices to reduce the burden of endoscopy in the context of preventive medicine. In the context of therapeutic interventions, there has been significant advancement in endoscopic techniques for the resection of early-stage cancer and the palliation of advanced malignancies. In the field of benign disease, novel techniques have been introduced to expand the endoscopic therapeutic portfolio for conditions such as gastro-oesophageal reflux disease, type 2 diabetes and obesity. This review addresses novel gastrointestinal procedures that have been developed or gained substantial evidence in the last 5 years, which are likely to impact clinical practice in the future.