评估尼日利亚拉各斯注射吸毒妇女对接触前预防艾滋病的认识和使用情况:横断面研究

Olanrewaju Onigbogi, Osadebamwen N Eghaghe, Modupe O Onigbogi, O. Ojo, Oluwatoyin Funmilola Babalola
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摘要

尼日利亚的女性注射吸毒者(WWID)比男性注射吸毒者更有可能感染艾滋病毒,并可能受益于暴露前预防疗法(PrEP)。因此,我们的研究试图确定尼日利亚拉各斯的注射吸毒妇女对 PrEP 的认识和使用情况。这项研究采用描述性横断面设计,通过滚雪球技术招募了 422 名参与者。研究使用访谈者发放的问卷收集数据,并使用 Epi Info 软件对数据进行分析,以频数表的形式呈现。研究使用 χ2 检验分析分类数据,研究分类变量之间的关系、关联性和独立性,显著性水平设定为 p<0.05。半数受访者(50.2%)失业,56.6%单身,7.8%了解 PrEP,只有 1.9%表示曾经使用过。年龄(p<0.038)、居住时间(p<0.001)和受教育程度(p<0.001)与对 PrEP 的了解程度有明显相关。对 PrEP 的认识提高与在当地政府辖区居住 1 年或以上(调整 OR (AOR) 0.20,95% CI 0.08 至 0.49)和至少完成中学教育(AOR 7.63,95% CI 2.59 至 22.45)相关。研究结果突出表明,有必要采取有针对性的干预措施,同时牢记在这一特定人口群体中使用 PrEP 的决定因素。解决 PrEP 使用的这些相关因素将对制定有效战略以减少艾滋病毒传播和改善这一弱势群体的总体健康状况起到关键作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessing awareness and utilisation of pre-exposure prophylaxis for HIV prevention among women who inject drugs in Lagos, Nigeria: a cross-sectional study
Women who inject drugs (WWID) in Nigeria are more likely to be living with HIV than their male counterparts and could benefit from pre-exposure prophylaxis (PrEP). Our study therefore sought to determine the awareness and use of PrEP among WWID in Lagos, Nigeria.The study was descriptive cross-sectional in design and involved 422 participants recruited by using the snowballing technique. Interviewer-administered questionnaires were used to collect data which were analysed using Epi Info software and presented as frequency tables. χ2test was used to analyse the categorical data and investigate relationships, associations, and independence between categorical variables with the level of significance set at p<0.05.There were 422 respondents with 60.2% of them between 18 and 30 years of age with the majority (90.1%) identifying as females while 6.9% identified as transgender. Half of the respondents (50.2%) were unemployed, 56.6% were single while 7.8% were aware of PrEP with only 1.9% reporting that they had ever used it. Factors significantly associated with awareness of PrEP were age (p<0.038), period of residence (p<0.001) and the level of education (p<0.001). Increased awareness of PrEP was associated with residence within the local government area for 1 year or more (adjusted OR (AOR) 0.20, 95% CI 0.08 to 0.49) and completion of at least secondary school education (AOR 7.63, 95% CI 2.59 to 22.45).This study sheds light on the crucial issue of awareness and utilisation of PrEP for HIV prevention among WWID in Lagos, Nigeria. The findings highlight the need for tailored interventions bearing in mind the determinants of PrEP use within this specific demographic group. Addressing these correlates of PrEP use will be pivotal in developing effective strategies to reduce HIV transmission and improve the overall health outcomes in this vulnerable population.
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