奥兰蒂皮瓣--治疗前尿道狭窄疾病的多功能选择:澳大利亚地区中心的技术和经验展示

K Ravichandran, W Harrison, D Desai
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引用次数: 0

摘要

目的在治疗前尿道狭窄疾病方面,泌尿科医生必须掌握多种技术,以应对该疾病的不同临床表现。Orandi 皮瓣是一种带有血管侧支的纵向阴茎腹侧皮瓣,可用于处理具有挑战性的缺血性狭窄和重新进行尿道成形术[1]。附带的视频对该技术的应用进行了演示和讨论。本研究还介绍了在一个地区中心取得的成果,证明了该技术在临床实践中的有效性。方法和手术过程 一位 77 岁的男性患有非闭塞性前尿道狭窄,曾进行过清洁的间歇性自我导尿和尿道扩张术,但均告失败。他因勃起功能障碍而植入了三片式阴茎假体,因此无法采用背侧入路进行尿道成形术。逆行尿道造影显示,尿道肉膜向近端延伸出一条 6 厘米长的狭窄。然后将皮瓣旋转到 IDC 上,并缝合到尿道板的右侧边缘。重新对龟头进行贴合,并缝合覆盖的皮肤。患者术后无并发症,排尿情况有所改善。患者术后没有继续进行清洁的间歇性自我导尿或进一步的尿道扩张。我们进行了一项前瞻性研究,以评估奥兰迪皮瓣术在恢复排尿功能方面的有效性,以及它对患者性功能和生活质量的影响。所有手术均由一家地区中心的一名受过重建研究员培训的泌尿科顾问医生实施。术前和术后评估包括尿流率测量和改良的患者报告结果调查。对所有接受奥兰蒂皮瓣手术的患者(n = 4)进行的前瞻性数据收集表明,没有并发症记录,也不需要尿道扩张或尿道成形术等进一步干预措施。对该患者群的分析表明,术后 3 个月时,最大流量(Qmax)平均提高了 316%,这肯定了疗效和结果的可重复性。所有患者在术后 3、6 和 12 个月的满意度均为 100%。它的耐用性使其能够应用于具有挑战性的情况,如重新进行尿道成形术和缺血性狭窄。该皮瓣可产生良好的疗效,如我们地区中心的疗效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Orandi flap—A versatile option for anterior urethral stricture disease and experience in a regional Australian centre

Objective

In regards to the treatment of anterior urethral stricture disease, a Urologist must possess diverse techniques tailored to address the varied clinical presentations of the entity. The Orandi flap, a longitudinal ventral penile skin flap with a vascular lateral pedicle lends its utilisation in tackling challenging ischemic strictures and re-do urethroplasty [1]. The technique is elucidated in the accompanying video providing a demonstration and discussion of its application. The study also presents the outcomes achieved at a regional centre, demonstrating its efficacy in clinical practice.

Methods and surgical procedure

A 77 year old male with a non-obliterative anterior urethral stricture, had failed clean intermittent self cathterisation and urethral dilatation. He has a three piece penile prosthesis inserted for erectile dysfunction therefore precluding a dorsal approach to urethroplasty. Retrograde urethrography revealed a 6 cm stricture extending proximally from the meatus.

The urethra is opened dorsally through the length of the stricture and the medial edge of the skin flap which has been dissected in sutured onto the left edge of the urethral plate. The skin flap is then rotated over the IDC and sutured onto the right edge of the urethral plate. Glans is re-approximated and the skin is closed overlying. The patient had no post operative complications and experienced improvement in voiding. The patient did not continue clean intermittent self-catheterisation or further urethral dilatation post operatively. A prospective study was conducted to evaluate the effectiveness of the Orandi flap procedure in reestablishing urinary function and its influence on patients' sexual function and quality of life. All surgeries were performed by a single reconstructive fellowship-trained consultant urologist at a regional centre. Pre and post operative assessments included uroflowmetry and modified patient reported outcomes measures survey.

Results

The favourable outcomes elicited in the presented patient was reproduced in the other patients treated at our regional centre. Prospective data collected on all patients undergoing Orandi flap (n = 4), demonstrated that no complications were recorded and no further interventions such as urethral dilatation or urethroplasty is required. Analysis of this patient cohort revealed an average improvement in maximum flow rate (Qmax) of 316 % at 3 months post procedure affirming the efficacy and reproducibility of the outcomes. 100 % of all patients were satisfied at 3,6 and 12 months.

Conclusion

The Orandi flap stands as a versatile and efficacious option for anterior urethral stricture disease. Its durability enables its application in challenging scenarios such as those of re-do urethroplasty and ischemic stricture. The flap yields favourable outcomes such as those evidenced at our regional centre.

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Urology video journal
Urology video journal Nephrology, Urology
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