在 316L 不锈钢基底上开发用于生物医学植入物的 PEEK 和 AgNP 复合涂层

1, 2024 Pub Date : 2024-03-06 DOI:10.46632/jmc/3/1/5
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引用次数: 0

摘要

生物医学植入物在现代医疗保健中发挥着至关重要的作用,但其长期成功与否取决于所使用的材料。本研究的重点是在 316L 不锈钢基底上开发聚醚醚酮(PEEK)和银纳米粒子(AgNP)的复合涂层,旨在增强其生物相容性和抗菌性能。PEEK 因其生物相容性和机械性能而闻名,而 AgNP 则具有出色的抗菌活性。通过将这些材料结合在一起,我们的目标是创造出一种涂层,它不仅能支持植入物与周围组织的整合,还能降低感染的风险,而感染是植入物手术中常见的并发症。制造过程包括在不锈钢基底上沉积 PEEK 层,然后使用电旋或浸渍涂层等合适的方法加入 AgNP。涂层基底将进行综合表征,包括机械测试、表面分析和抗菌效果评估。涂层的机械性能对于确保其在苛刻的人体环境中的耐用性和耐磨性至关重要。此外,还将对涂层的化学和生物特性进行评估,以确保其生物相容性和植入安全性。这项研究旨在促进生物医学植入物先进涂层的开发,最终提高植入物的性能和寿命。这项研究的成果将有助于开发更安全、更有效的生物医学植入物,造福全球患者和医疗保健系统。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Developing Composite Coating of PEEK and AgNP on 316L Stainless Steel Substrate for Biomedical Implant
Biomedical implants play a crucial role in modern healthcare, but their long-term success hinges on the materials used. This study focuses on developing a composite coating of polyetheretherketone (PEEK) and silver nanoparticles (AgNP) on 316L stainless steel substrates, aiming to enhance their biocompatibility and antibacterial properties. PEEK is known for its biocompatibility and mechanical properties, while AgNP exhibit excellent antibacterial activity. By combining these materials, we aim to create a coating that not only supports the integration of implants with surrounding tissue but also reduces the risk of infections, a common complication in implant surgery. The fabrication process involves depositing a PEEK layer on the stainless steel substrate, followed by the incorporation of AgNP using a suitable method such as electro spinning or dip coating. The coated substrates will undergo comprehensive characterization, including mechanical testing, surface analysis, and antibacterial efficacy assessment. The mechanical properties of the coating will be critical to ensure its durability and resistance to wear in the demanding environment of the human body. Furthermore, the chemical and biological properties of the coating will be evaluated to ensure its biocompatibility and safety for implantation. This study aims to contribute to the development of advanced coatings for biomedical implants, ultimately improving their performance and longevity. The findings of this research could lead to the development of safer and more effective biomedical implants, benefiting patients and healthcare systems worldwide.
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