过敏性结膜炎的病理生理学和治疗方法综述

Arvind Kumar Patel, P. Chandra, N. Sachan, Neha Singh
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引用次数: 0

摘要

过敏性疾病是一个严重的问题,影响着 40% 的人口。在临床实践中,最著名的视觉疾病无疑是视觉敏感症。专家们考虑到了遗传和污染等众多变量的影响。因此,本综述旨在提供有关过敏性结膜炎的病理生理学和治疗方法的详细描述。本研究通过对发表在 Pubmed、Science direct、Web of Science、Scopus 和 Google 等网站上的原始研究文章进行文献调查来完成。常年性过敏性结膜炎(PAC)和季节性过敏性结膜炎(SAC)的常见症状是哆嗦、流泪、分泌粘液和发红,但这些症状不会影响视力。然而,春季角膜结膜炎(VKC)和特应性角膜结膜炎(AKC)是最令人担忧的视觉过敏性结膜炎类型,它们会影响角膜,如果没有得到正确的认识和治疗,会损害视力。过敏性结膜炎的症状包括眼睛发痒、刺痛、发红以及睡觉时流黄色脓液。治疗过敏性结膜炎的主要目的是减轻和控制症状,提高生活质量。这包括尽量减轻瘙痒、发红、流泪、结膜或眼睑水肿以及其他相关病症。对于长期接触过敏原和久治不愈的患者来说,打破炎症模式和减轻炎症是额外的治疗目标。治疗过敏性结膜炎的药物包括肥大细胞稳定剂、皮质类固醇、抗组胺药、非甾体抗炎药、双效抗过敏药、抗白三烯类药物、抗 IgE 以及其他一些药物。治疗过敏性结膜炎的药物有很多种。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A review on pathophysiology and managements of allergic conjunctivitis
Allergic disorder is a serious issue affecting 40% of the population. The most well-known visual illness in clinical practise is undoubtedly visual sensitivity. The impact of numerous variables, including genetics and pollution, is taken into account by experts. Therefore, this review is intends to provide the detailed description related to pathophysiology and managements of allergic conjunctivitis.The study was performed by literature survey of original research articles published in Pubmed, Science direct, Web of Science, Scopus and Google etc.The two primary types of allergic conjunctivitis are perennial allergic conjunctivitis (PAC) and seasonal allergic conjunctivitis (SAC). The common effects of SAC and PAC are shivers, weeping, mucus production, and redness; nonetheless, these structures do not impair vision. However, vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC) are the most alarming types of visual allergic conjunctivitis, which impact the cornea and can impair vision if not properly recognised and treated. Allergic conjunctivitis symptoms include itchy, stinging red eyes and yellow pus during sleep. The major objectives of treatment for allergic conjunctivitis are to lessen and manage symptoms and raise quality of life. This involves minimising itchiness, as well as redness, tears, edoema of the conjunctiva or the eyelids, and other related disorders. Breaking the pattern of inflammation and reducing it are additional therapy objectives for patients with chronic allergen exposure and persistent illness. Mast cell stabilisers, corticosteroids, antihistamines, NSAIDs, dual-acting antiallergics, anti-leukotrienes, anti-IgE, and some other drugs are used to treat allergic conjunctivitis.There are the different types of allergic conjunctivitis among which the more prevalence types of allergic conjunctivitis are SAC and PAC while the more severe types are VKC and AKC. There are different types of medicines available for treatment of allergic conjunctivitis.
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