无论患者年龄多大,任何严重程度的弱视都可以完全治愈吗?

Sameera Irfan, Nausherwan Aadil, R. P. Maurya, Mohammad Saqib
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引用次数: 0

摘要

: :了解任何严重程度弱视的视力改善程度和所需时间:了解视力改善程度是否受患者发病年龄的影响:注意视力恢复程度是否受先前弱视治疗的影响。注意治疗后视力是否会随着时间的推移而下降。注意全日制遮盖疗法的并发症,尤其是遮盖性弱视。 在一项前瞻性干预研究中,连续纳入了 1701 例视力不良患者,不论患者年龄大小。在配戴屈光矫正器 8-12 周后,BCVA 没有进一步改善的情况下,患者开始接受弱视治疗,包括对好眼进行全时遮盖,同时积极使用弱视眼,每天至少阅读和书写 6 小时。每周进行两次定期随访。治疗的终点是使弱视眼的视力达到与好眼相同的水平。补片后定期随访 1-3 年。每组患者在治疗开始和结束时的视力比较采用配对 t 检验进行统计分析。 男性 896 例,女性 805 例。1383例(81.3%)曾接受过失败的弱视治疗。49例(2.9%)因治疗依从性差或随访不完整而退出研究。为简化结果分析,1701 例病例被分为三个年龄组:A 组:4-7 岁(473 例);B 组:8-12 岁(618 例);C 组:13-46 岁(610 例)。A 组和 B 组的总体成功率为 98%,C 组为 96.9%。任何严重程度和年龄的弱视都有可能完全恢复视力。患者发病时的年龄不应妨碍治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is amblyopia of any severity fully treatable, irrespective of a patient’s age?
: : To find out the level of visual improvement and the time it takes in amblyopia of any severity. : To find out whether the level of visual improvement is influenced by a patient's age at presentation. : To note whether the level of visual recovery is influenced by previous amblyopia therapy. To note any regression of visual acuity with time after initial improvement by therapy. To note complications of full-time occlusion therapy, especially occlusion amblyopia.: In a prospective interventional study, 1701 consecutive cases with poor vision were included irrespective of a patient’s age. After wearing refractive correction for 8-12 weeks and no further improvement in the BCVA, amblyopia therapy was started comprising of full-time patching of the good eye along with active use of the amblyopic eye by reading and writing at least 6 hours daily. Regular two weekly follow-ups were conducted. The endpoint of therapy was achieving a BCVA equal to that of the good eye. A regular post-patching follow-up was conducted for 1-3 years. Statistical analysis comparing the visual acuity at the start and the end of therapy was performed by a paired t-test for each group. : There were 896 male and 805 female cases. 1383 cases (81.3%) had previously failed amblyopia therapy. 49 cases (2.9%) dropped out of the study due to poor compliance with therapy or an incomplete follow-up. For a simplified analysis of results, the 1701 cases were divided into three age groups: Group A: age 4-7 years (473 cases), Group B: age 8-12 years (618 cases) and Group C: age 13-46 years (610 cases). The overall success in Group A and B cases was 98% and 96.9% in Group C cases. Full visual recovery is possible in amblyopia of any severity and age. The age of a patient at presentation should not preclude therapy.
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