基于 "Kavalgine "粘土的新型制剂在预防性皮肤护理中的抗菌潜力

Gagik Nersisyan, M. Melkumyan, B. Babayan, A. Grigoryan, Armen Grigoryan, A. Mikaelyan
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引用次数: 0

摘要

医药、兽医、农业等领域对新型抗菌制剂的需求量很大。然而,从类固醇、低聚/宏观环内酯和抗生素中提取的许多传统制剂都有明显的缺点:对人体健康有不利影响,可能对生态造成危害等。此外,环境中抗生素浓度的增加也加剧了多重耐药性问题。因此,需要在这方面进行创新,特别是寻找新的天然制剂替代品。本文讨论的 "Kavalgine "新制剂是利用天然成分开发的:在食盐开采过程中获得的高矿化度粘土、蜂胶、月桂精油和其他生物活性添加剂。该制剂成功地对各种机会性病原体的模式菌株进行了效果测试:肺炎克雷伯菌、铜绿假单胞菌、肠炎沙门氏菌和金黄色葡萄球菌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ANTIMICROBIAL POTENTIAL OF "KAVALGINE" CLAY BASED NOVEL PREPARATION FOR PROPHYLACTIC SKIN CARE
The demand for novel antimicrobial preparations is high in medicine, veterinary, agriculture, etc. However, numerous classical preparations derived from steroids, oligo-/macro- cyclic lactones, and antibiotics possess notable disadvantages: adverse effects on human health, the potential for ecological risks, etc. Moreover, the increase of antibiotic concentrations in environment escalates the multi-drug resistance problem. Therefore, the need of innovations in that scope, and particularly, the search for alternative new natural preparations is very actual. The current paper discusses "Kavalgine” new preparation, developed using natural components: highly mineralized clay obtained during the table salt mining; propolis, laurel essential oil and other bioactive additives. Its effect was successfully tested on model strains of various opportunistic pathogens: Klebsiella pneumonia, Pseudomonas aeruginosa, Salmonella enteritidis, and Staphylococcus aureus.
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