用 COMOC-MG 缝合线压迫子宫肌层和闭塞子宫动脉治疗失张力性产后出血的效果

Trupangi J. Chaudhari
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摘要

背景:产后出血(PPH)仍然是全球孕产妇发病率和死亡率的重要原因,而子宫失弛缓症是主要的致病因素。这项前瞻性介入研究旨在评估通过 COMOC-MG 缝合技术压迫子宫肌层和闭塞子宫动脉治疗无张力 PPH 的效果:2020年12月至2022年7月,在古吉拉特邦布吉的GK综合医院开展了一项前瞻性研究。该研究共招募了 100 名接受复杂剖腹产或阴道分娩的孕妇,她们均无已确定的风险因素。研究组采用 COMOC-MG 缝合技术,对照组采用标准无张力 PPH 处理。结果包括成功率、输血需求、并发症和死亡率:研究组(50 人)的人口统计学特征与对照组相当。值得注意的是,COMOC-MG 组的顺产成功率(100%)和剖宫产成功率(95.3%)高于对照组(分别为 72.7% 和 60.7%)。据观察,COMOC-MG 组的输血需求较低(34% 对 48%),并发症较少。产后第1天的血红蛋白(Hb)水平无明显差异:研究表明,COMOC-MG 缝合技术能有效处理无张力型 PPH,显示出卓越的成功率,并有可能减少输血需求。虽然还需要进一步的研究,包括更大规模的试验,但这些发现强调了 COMOC-MG 作为产科护理创新干预措施的前景,为产妇的预后提供了潜在的益处。观察到的安全性也支持将其应用于临床实践。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effectiveness of compression of myometrium and occlusion of uterine artery by COMOC-MG suture in management of atonic postpartum hemorrhage
Background: Postpartum haemorrhage (PPH) remains a significant cause of maternal morbidity and mortality globally, with uterine atony being a primary etiological factor. This prospective interventional study aimed to assess the effectiveness of the compression of myometrium and occlusion of uterine artery by COMOC-MG suture technique in managing atonic PPH. Methods: A prospective study was conducted at GK general hospital, Bhuj, Gujarat, from December 2020 to July 2022. The study enrolled 100 pregnant women without identified risk factors undergoing complicated caesarean or vaginal deliveries. The COMOC-MG suture technique was employed for the study group, while the control group received standard atonic PPH management. Outcomes included success rates, blood transfusion needs, complications, and mortality. Results: The study group (n=50) demonstrated comparable demographic characteristics to the control group. Notably, the COMOC-MG group exhibited higher success rates in normal (100%) and cesarean deliveries (95.3%) compared to the control group (72.7% and 60.7%, respectively). Lower blood transfusion needs (34% vs. 48%) and fewer complications were observed in the COMOC-MG group. Hemoglobin (Hb) levels on post-partum day 1 showed no significant difference. Conclusions: The study suggests that COMOC-MG suture technique is effective in managing atonic PPH, showing superior success rates and potentially reducing blood transfusion needs. While further research, including larger trials, is warranted, these findings underscore promise of COMOC-MG as an innovative intervention in obstetric care, offering potential benefits in maternal outcomes. The observed safety profile supports its consideration in clinical practice.
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