基于深度学习的人工耳蜗植入电极阵列定位统一框架。

Yubo Fan, Jianing Wang, Yiyuan Zhao, Rui Li, Han Liu, Robert F Labadie, Jack H Noble, Benoit M Dawant
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引用次数: 0

摘要

人工耳蜗(CI)是一种神经义肢,可以为重度到永久性听力损失患者提供声音感知。CI 包含一个电极阵列 (EA),在手术中被穿入耳蜗。最近的研究表明,听力效果与电极阵列的位置有关。图像引导人工耳蜗植入编程技术就是基于这种相关性,并利用 EA 位置与耳蜗内解剖结构的关系,帮助听力学家调整 CI 设置以改善听力。在术后 CT 图像中定位 EA 的自动化方法对于大规模研究和转化为临床工作流程具有重大意义。在这项工作中,我们提出了一种基于深度学习的统一框架,用于自动 EA 定位。它由一个多任务网络和一系列后处理算法组成,用于定位各种类型的 EA。在一个包含 27 个尸体样本的数据集上进行的评估表明,其定位误差略小于最先进的方法。另一项评估是在一个大规模临床数据集上进行的,该数据集包含两个机构的 561 个病例,结果表明与最先进的方法相比,该方法的鲁棒性有了显著提高。这表明这项技术可以整合到临床工作流程中,为听力学家提供有助于植入程序设计的信息,从而改善患者护理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Unified Deep-Learning-Based Framework for Cochlear Implant Electrode Array Localization.

Cochlear implants (CIs) are neuroprosthetics that can provide a sense of sound to people with severe-to-profound hearing loss. A CI contains an electrode array (EA) that is threaded into the cochlea during surgery. Recent studies have shown that hearing outcomes are correlated with EA placement. An image-guided cochlear implant programming technique is based on this correlation and utilizes the EA location with respect to the intracochlear anatomy to help audiologists adjust the CI settings to improve hearing. Automated methods to localize EA in postoperative CT images are of great interest for large-scale studies and for translation into the clinical workflow. In this work, we propose a unified deep-learning-based framework for automated EA localization. It consists of a multi-task network and a series of postprocessing algorithms to localize various types of EAs. The evaluation on a dataset with 27 cadaveric samples shows that its localization error is slightly smaller than the state-of-the-art method. Another evaluation on a large-scale clinical dataset containing 561 cases across two institutions demonstrates a significant improvement in robustness compared to the state-of-the-art method. This suggests that this technique could be integrated into the clinical workflow and provide audiologists with information that facilitates the programming of the implant leading to improved patient care.

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