SARS 和 COVID-19 的出现以及为下一次新出现的疾病 X 做好准备。

IF 3.9 3区医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL

Frontiers of Medicine Pub Date : 2024-02-01 Epub Date: 2024-04-02 DOI:10.1007/s11684-024-1066-6

Ben Hu, Hua Guo, Haorui Si, Zhengli Shi

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引用次数: 0

摘要

严重急性呼吸系统综合征（SARS）和冠状病毒病 2019（COVID-19）是本世纪新出现的两种人类冠状病毒疾病，对公众健康构成巨大威胁，并造成了巨大的生命和经济损失。在这篇综述中，我们回顾了追溯SARS-CoV分子进化的研究，并梳理了目前关于SARS-CoV-2潜在祖先的研究成果。我们还收集了有关在野生动物中发现的 SARS-CoV-2 类病毒、动物对 SARS-CoV-2 的易感性以及 SARS 相关冠状病毒（SARSr-CoVs）种间传播风险的最新知识。最后，我们讨论了如何应对未来新出现或再次出现的冠状病毒爆发的策略。

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Emergence of SARS and COVID-19 and preparedness for the next emerging disease X.

Severe acute respiratory syndrome (SARS) and Coronavirus disease 2019 (COVID-19) are two human Coronavirus diseases emerging in this century, posing tremendous threats to public health and causing great loss to lives and economy. In this review, we retrospect the studies tracing the molecular evolution of SARS-CoV, and we sort out current research findings about the potential ancestor of SARS-CoV-2. Updated knowledge about SARS-CoV-2-like viruses found in wildlife, the animal susceptibility to SARS-CoV-2, as well as the interspecies transmission risk of SARS-related coronaviruses (SARSr-CoVs) are gathered here. Finally, we discuss the strategies of how to be prepared against future outbreaks of emerging or re-emerging coronaviruses.

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来源期刊

Frontiers of Medicine ONCOLOGYMEDICINE, RESEARCH & EXPERIMENTAL&-MEDICINE, RESEARCH & EXPERIMENTAL

CiteScore

18.30

自引率

0.00%

发文量

800

期刊介绍： Frontiers of Medicine is an international general medical journal sponsored by the Ministry of Education of China. The journal is jointly published by the Higher Education Press and Springer. Since the first issue of 2010, this journal has been indexed in PubMed/MEDLINE. Frontiers of Medicine is dedicated to publishing original research and review articles on the latest advances in clinical and basic medicine with a focus on epidemiology, traditional Chinese medicine, translational research, healthcare, public health and health policies.