减肥手术的长期效果:黎巴嫩一家三级医院为期八年的研究

Rana Ibrahim , Abbas Fadel , Layal Ahmad , Hajar Ballout , Houssein Haidar Ahmad
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引用次数: 0

摘要

背景肥胖管理是一项长期挑战。我们的目标是调查减肥手术的各个方面,如并发症、合并症、感染率、体重减轻的长期可持续性,以及预测术后长期体重减轻的因素。结果这项研究的参与者平均年龄为 36.4 岁 (±12.1),手术前体重指数为 44.5 kg/m² (±7.5)。超重率(%EWL)在第三年达到峰值,为 75.09%,而总减重率(%TWL)在两年后保持在 33.41%。在 2 型糖尿病患者中,5 年后停药率达到 26.3%。零泄漏、主要并发症发生率低、无死亡病例。在长达 7 年的随访中,40% 的患者体重出现反弹。多变量分析表明,年龄和术前体重指数是影响三年后 EWL 百分比的负相关重要预测因素,标准化贝塔系数分别为-0.488(p = 0.001)和-0.450(p < 0.001)。结论减肥手术是公认的安全、有效的减轻体重和减少并发症的手术,主要并发症的发生率相对较低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Long-term outcomes of bariatric surgery: An eight-year study at a tertiary care hospital in Lebanon

Background

Obesity management presents a persistent challenge. Bariatric surgery, recognized for its transformative impact on weight loss and comorbidities, demands a thorough examination of its long-term implications.

Objectives

Our goal is to investigate different aspects of bariatric surgery, such as complications, comorbidities, infection rates, the long-term sustainability of weight loss, and factors predicting weight loss over an extended period following the procedure.

Setting

This study involves 100 patients who underwent primary bariatric surgery.

Methods

a sophisticated Longitudinal Observational Study design. With a Retrospective Component and a Follow-Up Component spanning eight years.

Results

The study included participants with a mean age of 36.4 years (±12.1) and a pre-surgery BMI of 44.5 kg/m² (±7.5). Excess Weight Loss (%EWL) peaked at 75.09 % by the third year, while Total Weight Loss (%TWL) sustained at 33.41 % after two years. Among individuals with type 2 diabetes, medication discontinuation rates reached 26.3 % at 5 years. Zero leaks, a low incidence of major complications and no incidence of mortality have been noted. In an extended 7-year follow-up, 40 % of patients experienced weight regain. Multivariate analyses identified age and preoperative BMI as negatively associated significant predictors impacting %EWL at three years, with standardized beta coefficients of −0.488 (p = 0.001) and −0.450 (p < 0.001), respectively. Conversely, smoking and Type 2 Diabetes Mellitus exhibited positive associations, with standardized beta coefficients of 0.336 (p = 0.004) and 0.286 (p = 0.063), respectively.

Conclusions

Bariatric surgery is acknowledged as a safe and efficacy procedure for reducing weight and comorbidities, with a relatively low incidence of major complications.

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