基于排序集抽样的平均剩余寿命递减估计,并应用于生存分析。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Elham Zamanzade, Ehsan Zamanzade, Afshin Parvardeh
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引用次数: 0

摘要

在给定的时间 t,种群中一个单位的平均剩余寿命(MRL)是在时间 t 仍存活的种群单位的平均剩余寿命。因此,改进 MRL 函数估计的一个自然方法就是在估计过程中使用这一假设。在本文中,我们在排序集抽样(RSS)中开发了一种 MRL 估计器,它具有单调性特性。我们证明它是真正 MRL 函数的强均匀一致估计器。我们还证明,引入的估计器的渐近分布与经验分布相同,因此,至少在渐近意义上,新估计器是 "免费 "获得的。然后,我们利用蒙特卡罗模拟将所提出的估计器与 RSS 和简单随机抽样 (SRS) 中的竞争对手进行了比较。我们的模拟结果证实了所提出的程序在有限样本量下的优越性。最后,我们使用了来自美国国家癌症研究所(NCI)的监测、流行病学和最终结果(SEER)项目的真实数据集,以证明所引入的技术能更准确地估计乳腺癌患者的平均剩余寿命。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Estimation of a decreasing mean residual life based on ranked set sampling with an application to survival analysis.

The mean residual lifetime (MRL) of a unit in a population at a given time t, is the average remaining lifetime among those population units still alive at the time t. In some applications, it is reasonable to assume that MRL function is a decreasing function over time. Thus, one natural way to improve the estimation of MRL function is to use this assumption in estimation process. In this paper, we develop an MRL estimator in ranked set sampling (RSS) which, enjoys the monotonicity property. We prove that it is a strongly uniformly consistent estimator of true MRL function. We also show that the asymptotic distribution of the introduced estimator is the same as the empirical one, and therefore the novel estimator is obtained "free of charge", at least in an asymptotic sense. We then compare the proposed estimator with its competitors in RSS and simple random sampling (SRS) using Monte Carlo simulation. Our simulation results confirm the superiority of the proposed procedure for finite sample sizes. Finally, a real dataset from the Surveillance, Epidemiology and End Results (SEER) program of the US National Cancer Institute (NCI) is used to show that the introduced technique can provide more accurate estimates for the average remaining lifetime of patients with breast cancer.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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