肥胖是心血管疾病的风险因素吗?

IF 3.6 2区 心理学 Q1 PSYCHOLOGY, MULTIDISCIPLINARY
Robert W. Jeffery
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引用次数: 0

摘要

本文回顾了心血管疾病(CVD)与肥胖之间关系的研究。大量证据有力地表明,肥胖与血压升高、胆固醇升高和葡萄糖不耐受有因果关系,而这些都是心血管疾病的主要风险因素。然而,将肥胖与心血管疾病本身联系起来的数据却不太一致。一些研究显示,肥胖与心血管疾病的发病率和死亡率之间存在正相关和分级关系,而另一些研究则显示两者之间没有影响,甚至存在反向关系。本文讨论了这些相互矛盾的研究结果的可能原因。这些原因包括肥胖的异质性,特别是中心性肥胖与外周性肥胖;由于使用不准确的肥胖指数而造成的个体分类错误;在估算肥胖作为复杂因果链中的一个变量所造成的影响时存在分析困难;以及存在诸如吸烟等混杂因素,这些因素会降低体重,但本身也是心血管疾病的诱因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is Obesity a Risk Factor for Cardiovascular Disease?
This article reviews research on the relationship between cardiovascular disease (CVD) and obesity. A preponderance of evidence strongly suggests that obesity is causally related to elevated blood pressure, elevated cholesterol, and glucose intolerance, all of which are primary risk factors for CVD. Nevertheless, data linking obesity to CVD itself are less consistent. While some studies show a positive and graded relationship between obesity and CVD incidence and mortality, others show no effect or even an inverse relationship. Possible reasons for these conflicting findings are discussed. These include heterogeneity of obesities, particularly central versus peripheral obesity; misclassification of individuals due to use of inaccurate obesity indices; analytic difficulties in estimating the contributions of obesity as a single variable in a complex chain of causation; and the presence of confounders such as cigarette smoking that lower weight, but are themselves a cause of CVD.
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来源期刊
Annals of Behavioral Medicine
Annals of Behavioral Medicine PSYCHOLOGY, MULTIDISCIPLINARY-
CiteScore
7.00
自引率
5.30%
发文量
65
期刊介绍: Annals of Behavioral Medicine aims to foster the exchange of knowledge derived from the disciplines involved in the field of behavioral medicine, and the integration of biological, psychosocial, and behavioral factors and principles as they relate to such areas as health promotion, disease prevention, risk factor modification, disease progression, adjustment and adaptation to physical disorders, and rehabilitation. To achieve these goals, much of the journal is devoted to the publication of original empirical articles including reports of randomized controlled trials, observational studies, or other basic and clinical investigations. Integrative reviews of the evidence for the application of behavioral interventions in health care will also be provided. .
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