金催化分子间赫克反应的异常选择性

IF 2.1 4区工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR

Gold Bulletin Pub Date : 2024-03-25 DOI:10.1007/s13404-024-00342-w

Mahesh Bhagwan Thoke, Nitin T. Patil

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引用次数: 0

摘要

Heck 反应一直被认为是烯烃和芳基卤化物发生交叉偶联反应生成烯烃的有效方法。然而，最重要的要求是必须有电子偏置的烯烃，并且需要引导基团来控制 Heck 反应的区域选择性。Patil 和 Gandon 研究小组最近记录了金催化的 Heck 反应，证明了可以利用简单的脂肪族烯烃作为底物。与其他过渡金属催化剂催化的 Heck 反应相比，这种方法不需要电子偏置烯烃，而且具有明显的区域选择性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Unusual selectivity in gold-catalyzed intermolecular Heck reactions

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Unusual selectivity in gold-catalyzed intermolecular Heck reactions

The Heck reaction has been considered a robust method for the cross-coupling reaction of olefins and aryl halides to yield alkenes. However, the most significant requirement is the necessity of electronically biased olefins and the requirement of directing group to control the regioselectivity of the Heck reaction. The research group of Patil and Gandon recently documented the gold-catalyzed Heck reaction, demonstrating the utilization of simple aliphatic alkenes as substrates. This approach does not need electronically biased olefins and offers a distinct regioselectivity when compared to the Heck reaction catalyzed by other transition metal catalysts.

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来源期刊

Gold Bulletin Chemistry-Inorganic Chemistry

CiteScore

3.70

自引率

4.50%

发文量

期刊介绍： Gold Bulletin is the premier international peer reviewed journal on the latest science, technology and applications of gold. It includes papers on the latest research advances, state-of-the-art reviews, conference reports, book reviews and highlights of patents and scientific literature. Gold Bulletin does not publish manuscripts covering the snthesis of Gold nanoparticles in the presence of plant extracts or other nature-derived extracts. Gold Bulletin has been published over 40 years as a multidisciplinary journal read by chemists, physicists, engineers, metallurgists, materials scientists, biotechnologists, surface scientists, and nanotechnologists amongst others, both within industry and academia. Gold Bulletin is published in Association with the World Gold Council.