癫痫患者的后可逆性脑病综合征:血压、头颅受累和癫痫复发之间的关系。

IF 2 4区 医学 Q2 OBSTETRICS & GYNECOLOGY
Gynecologic and Obstetric Investigation Pub Date : 2024-01-01 Epub Date: 2024-03-25 DOI:10.1159/000538519
Musa Temel, Merve Durmuş, Şeyma Eroğlu Durmaz, Deniz Güvenir, Erdem Gürkaş
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引用次数: 0

摘要

目的:后可逆性脑病综合征(PRES)是一种以头痛、癫痫发作、脑病、视力障碍和局灶性神经功能缺损为特征的临床影像学疾病。妊娠高血压是PRES的重要危险因素,可能会导致孕妇严重的发病率和死亡率:研究对象/材料、环境、方法:注意入院时的血压、脑血管源性水肿区域的数量以及反复发作的情况。患者分为三组:轻度、中度和重度:通过 Kruskal-Wallis 和 Pearson Chi-square 检验,各组间颅骨受累情况无统计学意义(P:0.471)。然而,二元逻辑回归分析表明,癫痫复发率与血压相关性增加(P:0.04):PRES是一种罕见的综合征,与多种病因有关。在我们的研究中,只纳入了子痫导致的 PRES 患者。因此,纳入的患者人数有限(24 人):结论:轻度、中度或重度子痫患者均可能出现 PRES。需要通过磁共振成像进行评估以确诊。早期快速治疗对降低孕妇的发病率和死亡率至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Posterior Reversible Encephalopathy Syndrome in Eclamptic Patients: The Relationship between Blood Pressure, Cranial Involvement, and Seizure Recurrence.

Objectives: Posterior reversible encephalopathy syndrome (PRES) is a clinic radiological disorder characterized by headache, epileptic seizure, encephalopathy, visual impairment, and focal neurological deficits. Gestational hypertension, which is a significant risk factor for PRES, may cause significant morbidity and mortality among pregnant women.

Design: Twenty-four patients with PRES caused by eclampsia who were admitted to our hospital in the last 5 years were included in this study.

Participants/materials, setting, methods: Blood pressure at admission, the number of regions with vasogenic edema in the brain, and recurrent seizures were noted. Patients were divided into three groups: mild, moderate, and severe.

Results: Using Kruskal-Wallis and Pearson χ2 tests, there was no statistical significance between the groups in terms of cranial involvement (p = 0.471). However, binary logistic regression analysis showed that seizure recurrence increased in correlation with blood pressure (p = 0.04).

Limitations: PRES is a rare syndrome associated with several etiologies. In our study, only patients with PRES due to eclampsia were included. Therefore, the number of included patients was limited (24 participants).

Conclusion: PRES may occur in eclamptic patients with mild, moderate, or severe blood pressure values. Evaluation by magnetic resonance imaging is needed to confirm the diagnosis. Early and rapid treatment is essential for reducing morbidity and mortality among pregnant women.

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来源期刊
CiteScore
4.20
自引率
4.80%
发文量
44
审稿时长
6-12 weeks
期刊介绍: This journal covers the most active and promising areas of current research in gynecology and obstetrics. Invited, well-referenced reviews by noted experts keep readers in touch with the general framework and direction of international study. Original papers report selected experimental and clinical investigations in all fields related to gynecology, obstetrics and reproduction. Short communications are published to allow immediate discussion of new data. The international and interdisciplinary character of this periodical provides an avenue to less accessible sources and to worldwide research for investigators and practitioners.
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