Shiyu Cheng, Han Gao, Yanli Li, Xiuting Shi, Xin Li, Tianzhuo Yang, Dan Teng, Tingzhu Meng, Jie Shi
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By univariate analyses, the results of the study showed that the incidence of postoperative DVT was significantly increased in cervical cancer patients complicated with old age, obesity, high preoperative plasma D-dimer level, increased preoperative triglyceride level, chronic diseases (hypertension, diabetes, and cardiovascular disease), open surgery, long operation time, intraoperative blood transfusion, advanced tumor stage, and preoperative chemotherapy/radiotherapy. Advanced age, obesity, elevated preoperative D-dimer level, high preoperative triglyceride level, and open surgery were independent risk factors for postoperative lower extremity DVT in patients with cervical cancer by multivariate regression analyses (all <i>P</i> < .05). In gynecologic patients with cervical cancer, there is a high incidence of postoperative lower extremity DVT. Clinicians should develop systematic and comprehensive prevention and treatment measures for the risk factors to lower this morbidity and improve patient prognosis.</p>","PeriodicalId":10335,"journal":{"name":"Clinical and Applied Thrombosis/Hemostasis","volume":"30 ","pages":"10760296241240747"},"PeriodicalIF":2.3000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10964453/pdf/","citationCount":"0","resultStr":"{\"title\":\"Analysis of Risk Factors of Postoperative Lower Extremity Deep Venous Thrombosis in Patients With Cervical Cancer.\",\"authors\":\"Shiyu Cheng, Han Gao, Yanli Li, Xiuting Shi, Xin Li, Tianzhuo Yang, Dan Teng, Tingzhu Meng, Jie Shi\",\"doi\":\"10.1177/10760296241240747\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Deep venous thrombosis (DVT) has a significant negative impact on surgical and tumor patient's safety and quality of life. 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引用次数: 0
摘要
深静脉血栓(DVT)对手术和肿瘤患者的安全和生活质量有很大的负面影响。目前还没有关于宫颈癌患者术后下肢深静脉血栓形成的发生率和风险因素的具体报告。分析宫颈癌患者术后深静脉血栓的危险因素对预防和治疗具有重要的临床意义。我们对湖北省宫颈癌防治中心收治的309例宫颈癌患者进行了回顾性分析,并采用Logistic回归模型检验了宫颈癌患者术后下肢深静脉血栓形成的风险变量。单变量分析结果显示,高龄、肥胖、术前血浆D-二聚体水平高、术前甘油三酯水平升高、慢性病(高血压、糖尿病、心血管疾病)、开放手术、手术时间长、术中输血、肿瘤晚期、术前化疗/放疗等并发症的宫颈癌患者术后深静脉血栓的发生率明显升高。通过多变量回归分析发现,高龄、肥胖、术前 D-二聚体水平升高、术前甘油三酯水平高和开胸手术是宫颈癌患者术后下肢深静脉血栓形成的独立危险因素(所有 P
Analysis of Risk Factors of Postoperative Lower Extremity Deep Venous Thrombosis in Patients With Cervical Cancer.
Deep venous thrombosis (DVT) has a significant negative impact on surgical and tumor patient's safety and quality of life. There was no specific report on the incidence and risk factors of postoperative lower extremity DVT in cervical cancer patients. Analysis of the risk factors of postoperative DVT in patients with cervical cancer is of great clinical significance for prevention and treatment. We retrospectively analyzed 309 cervical cancer patients treated by the Hubei Cervical Cancer Prevention Center and used a logistic regression model to test the risk variables of postoperative lower extremity deep venous thrombosis in cervical cancer patients. By univariate analyses, the results of the study showed that the incidence of postoperative DVT was significantly increased in cervical cancer patients complicated with old age, obesity, high preoperative plasma D-dimer level, increased preoperative triglyceride level, chronic diseases (hypertension, diabetes, and cardiovascular disease), open surgery, long operation time, intraoperative blood transfusion, advanced tumor stage, and preoperative chemotherapy/radiotherapy. Advanced age, obesity, elevated preoperative D-dimer level, high preoperative triglyceride level, and open surgery were independent risk factors for postoperative lower extremity DVT in patients with cervical cancer by multivariate regression analyses (all P < .05). In gynecologic patients with cervical cancer, there is a high incidence of postoperative lower extremity DVT. Clinicians should develop systematic and comprehensive prevention and treatment measures for the risk factors to lower this morbidity and improve patient prognosis.
期刊介绍:
CATH is a peer-reviewed bi-monthly journal that addresses the practical clinical and laboratory issues involved in managing bleeding and clotting disorders, especially those related to thrombosis, hemostasis, and vascular disorders. CATH covers clinical trials, studies on etiology, pathophysiology, diagnosis and treatment of thrombohemorrhagic disorders.