急性脑损伤的热管理:叙述性综述

IF 2.7 4区 医学 Q2 CRITICAL CARE MEDICINE
Eva Esther Tejerina Álvarez , José Ángel Lorente Balanza
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引用次数: 0

摘要

温度管理已被用于不同情况下导致的急性脑损伤患者,如心脏骤停后缺氧缺血性损伤、急性缺血性中风和严重创伤性脑损伤。然而,关于这种治疗策略对死亡率和功能预后的临床益处,目前的证据提供的结果并不一致,而且往往相互矛盾。目前的指南主要侧重于发热的积极预防和治疗,而治疗性低温疗法(TH)已不再使用,但根据应用方法和适当的患者选择,其有效性仍存在疑问。这篇叙述性综述介绍了治疗性低温对急性神经损伤患者影响的最相关临床证据,以及支持其使用的病理生理学概念。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Control térmico en el daño cerebral agudo: revisión narrativa

Temperature management has been used in patients with acute brain injury resulting from different conditions, such as post-cardiac arrest hypoxic-ischaemic insult, acute ischaemic stroke, and severe traumatic brain injury. However, current evidence offers inconsistent and often contradictory results regarding the clinical benefit of this therapeutic strategy on mortality and functional outcomes. Current guidelines have focused mainly on active prevention and treatment of fever, while therapeutic hypothermia (TH) has fallen into disuse, although doubts persist as to its effectiveness according to the method of application and appropriate patient selection. This narrative review presents the most relevant clinical evidence on the effects of TH in patients with acute neurological damage, and the pathophysiological concepts supporting its use.

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来源期刊
Medicina Intensiva
Medicina Intensiva CRITICAL CARE MEDICINE-
CiteScore
2.70
自引率
20.00%
发文量
146
审稿时长
33 days
期刊介绍: Medicina Intensiva is the journal of the Spanish Society of Intensive Care Medicine and Coronary Units (SEMICYUC) and of Pan American and Iberian Federation of Societies of Intensive and Critical Care Medicine. Medicina Intensiva has become the reference publication in Spanish in its field. The journal mainly publishes Original Articles, Reviews, Clinical Notes, Consensus Documents, Images, and other information relevant to the specialty. All works go through a rigorous selection process. The journal accepts submissions of articles in English and in Spanish languages. The journal follows the publication requirements of the International Committee of Medical Journal Editors (ICMJE) and the Committee on Publication Ethics (COPE).
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