甲基苯丙胺相关心肌病的风险因素和急诊室结果:病例对照研究

IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE
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引用次数: 0

摘要

背景甲基苯丙胺相关心肌病(MACM)是使用甲基苯丙胺的一种已知并发症;然而,人们对 MACM 患者的风险因素和预后并不十分了解。研究纳入了年龄≥18 岁、就诊指数包括有记录的甲基苯丙胺使用情况的急诊科患者。随访期间(3 个月至 3 年)记录有甲基苯丙胺使用的患者被视为病例(MACM)。对照组由有记录使用甲基苯丙胺但未发现 MACM 的患者按 2:1 的比例进行匹配。结果共发现9833名使用甲基苯丙胺的患者。其中,160 名使用甲基苯丙胺的患者与 322 名对照者进行了配对。平均年龄为 48.4 岁,143 名患者(29.7%)为女性。澳门巴黎人娱乐官网患者更有可能在就诊时入院(45.6% 对 34.8%,P = 0.021)。与澳门巴黎人娱乐官网相关的重要变量包括:首次就诊时入院(几率比 [OR] 1.51)、糖尿病(OR 3.02)、肾脏疾病(OR 5.47)和肺部疾病(OR 2.39)。澳门巴黎人娱乐官网患者在随访期间去急诊室就诊的次数更多(10.1 次对 7 次,P = 0.009),而且在所有就诊中入院率更高(32.5% 对 15.4%,P = 0.009)。此外,澳门巴黎人娱乐官网患者的住院时间明显长于对照组(平均增加 18 天,p = 0.009)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Risk Factors and Emergency Department Outcomes in Methamphetamine-Associated Cardiomyopathy: A Case-Control Study

Background

Methamphetamine-associated cardiomyopathy (MACM) is a known complication of methamphetamine use; however, risk factors and outcomes of patients with MACM are not well understood.

Study Objectives

This study aims to identify risk factors, emergency department (ED) interventions, and outcomes for MACM.

Methods

This case-control study was conducted between 2012 and 2020 at two academic EDs. ED patients ≥18 years with an index visit that included documented methamphetamine use were included. Patients with documented MACM during follow-up (3 months–3 years) were considered cases (MACM). A control group comprised of patients with documented methamphetamine use but no known MACM was matched at a 2:1 ratio. Logistic regression was used to model risk factors for MACM.

Results

A total of 9833 patients with methamphetamine use were identified. From this, 160 MACM patients were matched to 322 controls. The mean age was 48.4 years, and 143 patients (29.7%) were female. MACM patients were more likely to be admitted on their index visit (45.6% vs. 34.8%, p = 0.021). Significant variables associated with MACM included: admission at the index visit (odds ratio [OR] 1.51), diabetes (OR 3.02), kidney disease (OR 5.47), and pulmonary disease (OR 2.39). MACM patients had more ED visits in the follow-up period (10.1 vs. 7, p = 0.009) and were admitted at a higher rate across all visits (32.5% vs. 15.4%, p = 0.009). Additionally, MACM patients had significantly longer hospital stays than controls (mean 18 additional days, p = 0.009).

Conclusion

Patients who developed MACM had traditional risk factors for heart failure and experienced significantly more ED visits, more hospitalizations, and longer hospital stays than matched controls.

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来源期刊
Journal of Emergency Medicine
Journal of Emergency Medicine 医学-急救医学
CiteScore
2.40
自引率
6.70%
发文量
339
审稿时长
2-4 weeks
期刊介绍: The Journal of Emergency Medicine is an international, peer-reviewed publication featuring original contributions of interest to both the academic and practicing emergency physician. JEM, published monthly, contains research papers and clinical studies as well as articles focusing on the training of emergency physicians and on the practice of emergency medicine. The Journal features the following sections: • Original Contributions • Clinical Communications: Pediatric, Adult, OB/GYN • Selected Topics: Toxicology, Prehospital Care, The Difficult Airway, Aeromedical Emergencies, Disaster Medicine, Cardiology Commentary, Emergency Radiology, Critical Care, Sports Medicine, Wound Care • Techniques and Procedures • Technical Tips • Clinical Laboratory in Emergency Medicine • Pharmacology in Emergency Medicine • Case Presentations of the Harvard Emergency Medicine Residency • Visual Diagnosis in Emergency Medicine • Medical Classics • Emergency Forum • Editorial(s) • Letters to the Editor • Education • Administration of Emergency Medicine • International Emergency Medicine • Computers in Emergency Medicine • Violence: Recognition, Management, and Prevention • Ethics • Humanities and Medicine • American Academy of Emergency Medicine • AAEM Medical Student Forum • Book and Other Media Reviews • Calendar of Events • Abstracts • Trauma Reports • Ultrasound in Emergency Medicine
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