关于皮肤色素沉着的鉴别诊断问题:瘙痒症的临床病例

M. Ufimtseva, Y. Bochkarev, M. S. Efimova, K. Nikolaeva
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引用次数: 0

摘要

导言。发育障碍是一类广泛的疾病,包括遗传变异中的先天性形式,以及由皮肤或全身表现引起的继发性获得性形式。本刊物旨在展示皮肤色素沉着的鉴别诊断特征,以确定荨麻疹的临床表现。使用 eLibrary.Ru、Scopus、PubMed 等搜索引擎对国内外文献资料进行了查阅。在患者自愿知情同意的基础上,对医疗文件进行了分析,同时考虑了临床和病理数据以及实验室和仪器检查的结果。结果文章对文献进行了综述,并介绍了一例胸椎退行性萎缩性病变患者的神经痛临床病例。痛觉神经痛属于皮肤痛症的一个大类,是一种感觉神经病,其特征是在胸椎神经皮肤分支的神经支配区内,背部皮肤出现局部单侧瘙痒和色素沉着,多发于成年和老年女性。瘙痒症皮肤表现的非特异性和医生对这种疾病的认识不足会导致诊断和战术错误。不同程度的皮肤瘙痒是该病的主要症状,导致病情加重和患者生活质量下降。鉴于该病理学的跨学科性质,神经科医生、神经外科医生、皮肤病医生、全科医生、普通医生、肿瘤科医生和内分泌科医生可能会对这篇文章感兴趣。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
On the Question of Differential Diagnosis of Skin Hyperpigmentations: The Clinical Case of Notalgia Paresthetica
Introduction. Developmental disorders acquire an extensive group of diseases, including congenital forms in inheritance variants, as well as secondary acquired forms due to skin or systemic manifestations.The purpose of this publication is to demonstrate the features of the differential diagnosis of skin hyperpigmentation to identify the clinical manifestation of notalgia paresthetica.Materials and methods. A review of foreign and domestic literary sources was carried out using the search engines eLibrary.Ru, Scopus, PubMed. On the basis of the patient’s voluntary informed consent, an analysis of medical documentation was carried out, taking into account clinical and anamnestic data and the results of laboratory and instrumental examination. Results. The article presents a review of the literature, as well as a clinical case of notalgia paresthetica in a patient with degenerative-dystrophic changes in the thoracic spine.Discussion. Notalgia paresthetica belongs to a large group of cutaneous dysesthesias and is a sensory neuropathy characterized by localized unilateral itching and hyperpigmentation of the skin of the back in the zone of innervation of the cutaneous branches of the thoracic spinal nerves, affecting more often adult and elderly women. The nonspecificity of skin manifestations of notalgia paresthetica and the low awareness of doctors about this disease can lead to diagnostic and tactical errors. Skin itching of varying intensity is the main symptom of the disease, leading to an accentuation of its disease and a decrease in the quality of life of patients.Conclusion. Given the interdisciplinary nature of the pathology, the article may be of interest to neurologists, neurosurgeons, dermatovenereologists, general practitioners, general practitioners, oncologists, and endocrinologists.
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