尼日利亚阿卡的视网膜色素变性:一项调查研究

Bernard Chukwunonyerem Ochiogu, Akunne Ijeoma Apakama, Anthonia Chinyelu Udeaja, Olufunmi Adebimpe Ijeoma Otuka, Arinze Anthony Onwuegbuna
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摘要

背景介绍视网膜色素变性症会导致不可逆的失明,男女均可患病,通常具有遗传性。研究目的描述尼日利亚阿卡 Chukwuemeka Odumegwu Ojukwu 大学教学医院眼科视网膜色素变性症的发病率和模式。材料和方法:对 2014 年 1 月至 2021 年 12 月期间在阿卡 Chukwuemeka Odumegwu Ojukwu 大学教学医院眼科就诊的所有新患者的病历进行了审查。筛选出临床诊断为视网膜色素变性的患者,并使用描述性统计学方法提取和分析了患者的年龄、性别、职业、病程、相关发病率和眼底检查结果等信息。结果在研究期间,眼科诊所共接诊了 5461 名新患者,其中 29 人(0.5%)被确诊为视网膜色素变性。在 29 名患者中,18 名(62.1%)为男性,11 名(37.9%)为女性,男女比例为 1.6:1。年龄范围为 7 岁至 69 岁。13 名患者(44.8%)的年龄介于 16 岁至 44 岁之间。中位年龄为 33 岁,平均年龄为 34.8+15.2岁。九名患者(31.0%)是学生。患者最常见的主诉是视力不佳(27 人,占 93.1%)和屈光不正(8 人,占 27.68%)。7 名患者(24.18)在就诊时已经失明,而视网膜色素沉着是最常见的眼底发现,共有 29 人(100%)。结论视网膜色素变性是导致视力受损和失明的原因之一,降低了患者的生活质量。应鼓励早期诊断和视觉康复。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Retinitis Pigmentosa in Awka, Nigeria: A Survey Study
Background: Retinitis pigmentosa which causes irreversible blindness and affects all gender is usually inherited. Objectives: To describe the incidence and pattern of retinitis pigmentosa at the Eye Unit of Chukwuemeka Odumegwu Ojukwu University Teaching Hospital Awka, Nigeria. Materials and Methods: The case files of all the new patients seen at the Eye Unit of the Chukwuemeka Odumegwu Ojukwu University Teaching Hospital Awka between January 2014 to December 2021 were reviewed. Those with clinical diagnosis of Retinitis Pigmentosa were selected and information bordering on age, sex, occupation, disease duration. associated morbidity and fundus findings were extracted and analyzed using descriptive statistics. Results: Out of the 5461 new patients seen at the Eye Clinic within the study period, 29(0.5%) were diagnosed of Retinitis Pigmentosa. Of the 29 patients 18 (62.1%) were males and 11(37.9%) females, with male to female ratio of 1.6:1. The age range was 7 years to 69 years. Thirteen patients (44.8%) were between 16 years and 44 years. Median age was 33 years while the mean age was 34. 8+15. 2 years. Nine (31.0%) patients were students. The most common complaints of the patients were poor vision, 27(93.1%) and refractive error 8(27.68). Seven patients (24.18) were blind at presentation while retinal pigmentation was the most frequent fundus finding 29 (100%). Conclusion: Retinitis Pigmentosa is a cause of visual impairment and blindness which reduces the quality of life of affected persons. Early diagnosis and visual rehabilitation should be encouraged.
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