Multiple Bccs after Lisinopril Intake – Significant Connections to The Drug Related Photo- (Nitroso)-Carcinogenesis in The Context of Oncopharmacogenesis

An 80-year-old female presented to the dermatology department due to an atrophic lesion in the area of the nasal apex, dating for the past 5-6 years. Moreover, there was a slowly developing tumor-like growth in her left temporal region, initially noticed 1-2 years ago. Over the last month, the formation began to bleed upon light touch. Furthermore, there was another lesion in the sacral area with an irregular hyperpigmented edge, also dating back 1-2 years. The patient denied having any allergies or family history of skin malignancies. Regarding comorbidities, she underwent cholecystectomy in 2016. She has been managing arterial hypertension with lisinopril dehydrate 10 mg once daily for the past 10 years. Additionally, she has been treating vertigo with a daily intake of betahistine dihydrochloride 16 mg for the same duration. She is also taking spironolactone 25 mg once daily at noon and diosmin 600 mg once daily at noon both for the past two months (prior to the consultation). The patient presented with a request for physical evaluation of the lesions and further therapeutic approach to be established.