太空中的双胞胎和端粒

Susan M. Bailey
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引用次数: 0

摘要

作为美国国家航空航天局双胞胎研究(NASA Twins Study)的一部分,我们对长期太空飞行期间端粒和DNA损伤反应(基因组稳定性)的相关调查对参与探索任务的宇航员的健康和表现以及长期衰老和疾病风险结果都有重要影响。这些结果将与 "双胞胎研究 "的其他调查一起,指导未来的研究和个性化医学方法的开发,以便在我们返回月球及更远的地方时评估对宇航员个人健康的影响。特别是随着未来几年太空旅行者甚至太空游客的数量和多样性的增加,确定个体差异对与太空旅行、探索以及最终居住在其他星球相关的极端环境、经历和慢性接触的反应,是确保未来宇航员在执行此类任务期间的表现和健康,以及在执行任务后改善疾病和衰老过程的下一个关键步骤。Ad astra!
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Twins And Telomeres-In Space!
As part of the NASA Twins Study, our investigations related to telomeres and DNA damage responses (genome stability) during long-duration spaceflight have important implications for the health and performance of astronauts participating in exploration missions, as well as for long-term aging and disease risk outcomes. Together with the other Twins Study investigations, results will guide future studies and development of personalized medicine approaches for evaluating health effects for individual astronauts as we make our way back to the moon and beyond. Particularly as the number and diversity of space travelers and even space tourists increases over the coming years, identifying individual differences in response to the extreme environment, experiences and chronic exposures associated with space travel, exploration, and eventual habitation of other planets, represents a critical next step for ensuring future astronaut performance and health during, and improving disease and aging courses following, such missions. Ad astra!
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