新型冠状病毒感染对心血管疾病发展的影响(系统综述)

N. E. Apartseva, A. D. Khudiakova
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引用次数: 0

摘要

2020 年,英国国家健康与护理卓越研究所提出了后科维德综合征的概念。后科维德综合征的主要表现之一是心血管疾病(CVD)和血脂异常。然而,COVID-19 康復者心血管疾病的發病模式仍不清楚。本系统性综述的目的是分析有关过去新型冠状病毒感染对后 COVID 时期血脂异常和动脉粥样硬化相关疾病(AAD)发展的贡献的研究数据。共选取了 106 篇文献进行分析。在排除了临床病例、药物研究、文献综述和专门论述 COVID-19 急性期的出版物后,从俄罗斯和国际搜索引擎上共筛选出 19 篇文章。研究分析得出的结论是,COVID-19 感染对新的急性呼吸道感染的发展和现有感染的恶化做出了重要贡献。这种现象最有可能的发生机制之一似乎是在 COVID-19 病程背景下内皮炎症的发展,但专门研究这一问题的著作并不多。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Contribution of new coronavirus infection to the development of cardiovascular diseases (systematic review)
In 2020, the National Institute for Health and Care Excellence in the UK   proposed   the concept of post-Covid syndrome. One of the main manifestations of the post-COVID syndrome are cardiovascular diseases (CVD) and dyslipidemia. However, the pathogenetic patterns of CVD development in COVID-19 convalescents remain unclear. The purpose of the systematic review was to analyze research data on the contribution of past new coronavirus infection to the development of dyslipidemia and atherosclerosis-associated diseases (AAD) in the post-COVID period. 106 publications were selected for analysis. After excluding clinical cases, drug studies, literature reviews and publications devoted to the acute period of COVID-19, a total of 19 articles were selected from Russian and international search engines. Analysis of studies has led to the conclusion that COVID-19 infection makes a significant contribution to the development of new AADs and worsening existing. One of the most likely mechanisms for occurrence of this phenomenon seems to be the development of endotheliitis against the background of the course of COVID-19, however, there are not enough works devoted to this problem.
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