在全十二指肠切除术后早期静脉注射胰岛素的患者中使用 Guardian Connect 血糖监测系统

IF 0.7 Q4 ENDOCRINOLOGY & METABOLISM
Diabetes Mellitus Pub Date : 2024-03-19 DOI:10.14341/dm13055
A. G. Farmanov, E. V. Bublik, O. Vinogradskaya, O. V. Udovichenko, A. Zilov, S. M. Deunezheva, E. G. Ryzhkova, V. I. Egorov, V. Fadeev, A. V. Zhivov, I. E. Tobianskaya
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引用次数: 0

摘要

背景:在不同亚型的胰源性糖尿病中,全十二指肠切除术(TDPE)术后患者的血糖控制最为困难,这首先是由于存在胰岛素绝对不足。材料与方法:分析了 26 名 TDPE 术后早期患者的血糖测量结果。其中 12 人使用了 Guardian Connect CGM 系统。在这组患者中,我们分析了 43 个 CGM 周期(1 个周期 - 6 天,共 258 天)和 971 次用于校准 CGM 的血糖仪测量值;在其他 14 名仅使用血糖仪的患者中,我们分析了 2496 次血糖值。我们计算了 6 天内使用 CGM 和仅使用血糖仪的成本效益(包括 CGM、血糖仪、一次性材料、医务人员控制血糖所需时间的诊所工资成本)。结果:与 2 号组相比,1 号组的血糖水平在 5.6 至 10.0 mmol/L 目标范围内(66.7% vs 61.2%,P=0.003)和 4.3-11.6 mmol/L 范围内(85.2% vs 82.2%,P=0.038)的人数更多。使用 Guardian Connect CGM 系统控制血糖一个周期(6 天)的成本分析和同期使用血糖仪控制血糖的成本分析表明,使用 Guardian Connect CGM 系统对接受静脉胰岛素治疗的 TDPE 后患者进行治疗,可减少门诊费用 21.结论:Guardian Connect CGM 系统证明了其在 CIVIT TDPE 术后早期患者血糖控制过程中的安全性和成本效益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Use of the Guardian Connect glycemic monitoring system in patients after total duodenopancreatectomy in the early postoperative period on intravenous insulin therapy
BACKGROUND: Among different subtypes of pancreatogenic diabetes mellitus the biggest difficulties of glycemic control arise in patients after total duodenopancreatectomy (TDPE), first of all due to the presence of absolute insulin insufficiency.AIM: Estimating safety and cost-effectiveness Guardian Connect CGM system in early postoperative period in hospitalized patients after TDPE on continuous intravenous insulin therapy (CIVIT).MATERIALS AND METHODS: Glucose measurement results of 26 patients in early postoperative period after TDPE were analyzed. In 12 of them, we used Guardian Connect CGM system. In this group 43 cycles (1 cycle — 6 days, 258 days total) of CGM and 971 glucometer measurements used for CGM calibration were analyzed; in other 14 patients in whom only glucometer was used we analyzed 2496 glycemic values.Cost-effectiveness was calculated over 6 days for CGM and only glucometer use (including cost of CGM, glucometers, disposable materials, clinic wage-costs to medical staff for time required for glucose control).RESULTS: Glucose levels of group #1 were in the target range 5.6 to 10.0 mmol/L (66.7 vs 61.2%, p=0.003) and the range 4.3–11.6 mmol/L (85.2% vs 82.2%, p=0.038) more than in comparison with group #2.The frequency of hypoglycemic episodes (<3.9 mmol/L) was statistically significantly lower in the CGM group (6 vs 54, p<0.001, RO 8.463 [3.579; 20.015], RR 1.746 [1.551; 1.966]).Cost analysis of glucose control using Guardian Connect CGM system for one cycle (6 days) and cost of glucose control using glucose meter for the same period showed that using Guardian Connect CGM system in patients after TDPE on intravenous insulin therapy reduced clinic costs by 21.7% in ICU and by 25.7% in the hospital department.CONCLUSION: Guardian Connect CGM have demonstrated its safety and cost-effectiveness during glucose control in patients in early postoperative period after TDPE on CIVIT.
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来源期刊
Diabetes Mellitus
Diabetes Mellitus ENDOCRINOLOGY & METABOLISM-
CiteScore
1.90
自引率
40.00%
发文量
61
审稿时长
7 weeks
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