Hayder M. Al-kuraishy, Salah Al-weendy, Ali k. Al-Buhadilly, Iman Al-bajajy, Ali Al-gareeb, Ammar Al-hafied
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引用次数: 0
摘要
与标准抗生素相比,蓖麻香草具有显著的抗菌活性,尤其是对革兰氏阴性细菌。我们选择了四个细菌属,其中两个为革兰氏阴性菌属(大肠杆菌和绿脓杆菌),两个为革兰氏阳性菌属(金黄色葡萄球菌和粪肠球菌)。对这些细菌进行培养,然后加入配制成酒精溶液和水溶液的蓖麻提取物,测定每种细菌十个分离物的 MIC(最小抑菌浓度)。结果表明,水提取物对所有选定细菌的 MIC 值介于 8-32 毫克/毫升之间,而醇提取物的 MIC 值介于 8-16 毫克/毫升之间。此外,酒精提取物的最低 MIC 值为 8 毫克/毫升,而水提取物的最低 MIC 值为 16 毫克/毫升。总之,酒精提取物和水提取物都能产生特定的 MIC,但酒精提取物的 MIC(8 毫克/毫升)更低,产生的效果更特别。因此,这些提取物的局部应用可作为敏感细菌的替代抗菌疗法。
ANTIBACTERIAL ACTIVITY OF RICINNUS COMMUNIS: IN VITRO STUDY
Ricinnus communis herb produces significant antimicrobial activity particularly against Gram negative bacteria, in comparison with standard antibiotics. Four bacterial genera were selected two Gram negative (Escherichia coli, and Pseudomonas aeruginosa); and two Gram positive (Staphylococcus aureus, Enterococcus fecalis). These bacterial isolates were incubated and subsequently adding Ricinus communis extracts which were prepared as alcoholic and aqueous solutions .The MIC (Minimal Inhibitory Concentration)was determined for ten isolates of each bacteria . Results showed that the MIC of aqueous extracts ranged between 8-32mg/ml for all selected bacteria while the MIC of the alcoholic extract ranged between 8-16mg/ml. Moreover; the lowest MIC of alcoholic extract was 8mg/ml while the lowest MIC for aqueous extract was 16mg/ml. In conclusion, the alcoholic and aqueous extract generates specific MIC, but the alcoholic extracts produce more particular effects by lower MIC (8 mg/ml). Thus; a topical application of these extracts are useful as alternative antimicrobial remedy regarding the sensitive bacteria.