{"title":"Vero 适应性减毒株与广谱型高致病性流感病毒株之间 LAIV 重配的梯形图分布","authors":"Ze Liu, Jinhai Huang, Gao Hui","doi":"10.23958/ijirms/vol09-i03/1818","DOIUrl":null,"url":null,"abstract":"It described the “ladder distribution” of live attenuated influenza vaccine (LAIV) reassortment between Vero cells adaption attenuated strain and wide type-high virulent influenza virus strains by the reverse genetics approach. That gene constellation could save the immunogenicity (imm) of the parental strain and make new reassort virus strain attenuation (att) characteristics for further vaccine using, rapidly, not only seasonal vaccine but also pandemic flu vaccine.","PeriodicalId":14008,"journal":{"name":"International Journal of Innovative Research in Medical Science","volume":"112 5","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Ladder Distribution of LAIV Reassortment between Vero Adaption Attenuated Strain and Wide Type Highly Virulent Influenza Virus Strain\",\"authors\":\"Ze Liu, Jinhai Huang, Gao Hui\",\"doi\":\"10.23958/ijirms/vol09-i03/1818\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"It described the “ladder distribution” of live attenuated influenza vaccine (LAIV) reassortment between Vero cells adaption attenuated strain and wide type-high virulent influenza virus strains by the reverse genetics approach. That gene constellation could save the immunogenicity (imm) of the parental strain and make new reassort virus strain attenuation (att) characteristics for further vaccine using, rapidly, not only seasonal vaccine but also pandemic flu vaccine.\",\"PeriodicalId\":14008,\"journal\":{\"name\":\"International Journal of Innovative Research in Medical Science\",\"volume\":\"112 5\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-03-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Innovative Research in Medical Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23958/ijirms/vol09-i03/1818\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Innovative Research in Medical Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23958/ijirms/vol09-i03/1818","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Ladder Distribution of LAIV Reassortment between Vero Adaption Attenuated Strain and Wide Type Highly Virulent Influenza Virus Strain
It described the “ladder distribution” of live attenuated influenza vaccine (LAIV) reassortment between Vero cells adaption attenuated strain and wide type-high virulent influenza virus strains by the reverse genetics approach. That gene constellation could save the immunogenicity (imm) of the parental strain and make new reassort virus strain attenuation (att) characteristics for further vaccine using, rapidly, not only seasonal vaccine but also pandemic flu vaccine.
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