治疗急性胆囊炎的内镜经胆囊支架植入术

Hassan A. Abdallah
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引用次数: 0

摘要

胆囊切除术是治疗急性胆囊炎的首选方法。然而,对患有严重并发症的高危患者进行急诊胆囊切除术的死亡率仍不能令人满意。内镜胆囊支架置入术(ETGBS)已成为治疗急性胆囊炎的一种有效的内镜介入技术。 本研究的目的是评估 ETGBS 治疗不适合手术的老年人急性胆囊炎的安全性和有效性。 我们对阿斯旺大学医院外科接受急性胆囊炎治疗的 35 名 60 岁或以上的老年患者进行了研究。每位患者都接受了 ETGBS,即在胆囊中插入一个 7 英尺的支架。如果 ETGBS 不成功,则进行经皮经肝胆囊引流术。ETGBS 的有效性是本次调查的主要结果指标。 有 30 例(85%)急性胆囊炎患者的 ETGBS 治疗获得成功。8.57%(3/35)的病例出现了早期不良事件(AE)。三名患者出现内镜括约肌切开术出血,一名患者出现轻微胰腺炎,一名患者出现阻塞性黄疸,这些都是早期不良反应。晚期 AE 占 8.57%(3/35)。晚期不良反应包括一名患者的胆管炎和另外两名患者的胆囊炎复发。ETGBS 治疗失败的五名患者采用了经皮经肝胆囊引流术。 对于不适合手术的急性胆囊炎老年患者来说,ETGBS 似乎是一种成功的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Endoscopic transpapillary gallbladder stenting for acute cholecystitis
Cholecystectomy is the treatment of choice for acute cholecystitis. However, the mortality rate of emergency cholecystectomy in high-risk patients with severe comorbidities remains unsatisfactory. Endoscopic transpapillary gallbladder stenting (ETGBS) has emerged as a useful interventional endoscopic technique for the management of acute cholecystitis. The purpose of this research was to assess the safety and effectiveness of ETGBS in the treatment of acute cholecystitis in elderly individuals who were not good candidates for surgery. We studied 35 elderly patients, 60 years of age or older, receiving treatment at Aswan University Hospital’s surgery department for acute cholecystitis. Every patient had ETGBS, involving the insertion of a 7-Fr stent into the gallbladder. If ETGBS was unsuccessful, percutaneous transhepatic gallbladder draining was carried out. The effectiveness of ETGBS was the primary outcome measure in this investigation. ETGBS was successful in 30 (85%) individuals with acute cholecystitis. 8.57% (3/35) of the cases had early adverse events (AEs). Three patients had endoscopic sphincterotomy hemorrhage, one had minor pancreatitis, and one patient experienced obstructive jaundice as early AEs. There were 8.57% (3/35) late AEs. Late AEs included cholangitis in one patient and cholecystitis recurrence in two others. Percutaneous transhepatic gallbladder drainage was used for the five individuals in whom ETGBS failed. ETGBS appears to be a successful treatment for elderly patients with acute cholecystitis who are unsuitable for surgery.
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