非黑色素瘤面部皮肤癌:切除和重建的手术规划

Nasr Al-Qadasi, Yahia Al-Sayaghi, Abdullfatah Al-tam, Raddad AL-Fakih
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引用次数: 0

摘要

非黑色素性筋膜皮肤癌最有效的治疗方法是手术切除。术前计划和对重建程序的透彻掌握,如初次闭合皮肤移植、局部组织瓣、远处组织瓣和游离组织转移,对于这些肿瘤的手术治疗至关重要。非黑色素瘤皮肤癌(NMSC)治疗方法的选择因人而异,受患者年龄、体型、组织学亚型和患病部位的影响。治疗的目的是消除病灶,同时保持正常的组织、功能和外观。本研究涵盖了面部特有的皮肤恶性肿瘤手术切除和重建的思路和方法。 这项研究涉及 98 名不同年龄和性别的患者。其中,89%的患者患有基底细胞癌,11%的患者患有鳞状细胞癌,这两种肿瘤都属于低危和高危肿瘤,其大小、位置和组织学亚型各不相同。低风险恶性肿瘤的切除安全边际为 3-5 毫米,高风险癌症的切除安全边际为 5-10 毫米。有 17 名患者采用了植皮手术(分厚植皮和全厚植皮)。56 名患者接受了局部推进、转位和旋转皮瓣;15 名患者接受了区域性插植皮瓣;6 名患者因颈部淋巴结浸润而接受了颈部阻断切除术,并将远处梗阻皮瓣作为背阔肌皮瓣;4 名患者接受了颈部阻断切除术和游离组织转移。 有 6 名患者出现了问题,包括 2 例部分移植物和皮瓣脱落、2 例伤口感染和 1 例疤痕回缩;不过,通过有针对性的护理,他们都恢复得很好。92%的患者认为美容效果令人满意,功能效果良好。 大面积切除和适当的手术重建是理想的治疗方式,可获得良好的美学效果或功能性结果,同时,正如这一系列连续治疗的患者所显示的那样,使用分层厚皮移植并不是首要任务,很多病例本可以使用局部皮瓣进行治疗。面部非多发性硬化症的治疗需要基本知识,对整形外科医生来说也是一项挑战,其基础是实现最佳的肿瘤、功能和美容效果。必须强调的是,NMSC 治疗后需要对患者进行教育和适当的肿瘤监测。对面部恶性肿瘤大样本的回顾可以为进一步的研究提供指导,这一点不容低估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nonmelanoma facial skin cancer: surgical planning for resection and reconstruction
The most effective treatment for nonmelanotic fascial skin cancer is surgical excision. Preoperative planning and a thorough grasp of reconstructive procedures, such as primary closure skin grafting, locoregional tissue flaps, remote tissue flaps, and free tissue transfer, are essential for the surgical therapy of these tumors. The choice of nonmelanoma skin cancer (NMSC) therapy is very specific to each patient and is influenced by the patient’s age, size, histologic subtype, and location of the disease. Treatment is to obliterate the lesion while maintaining normal tissue, function, and appearance. The ideas and methods of surgical excision and reconstruction of skin malignancies unique to the face were covered in this study. This study involved 98 patients of various ages and sexes. Of them, 89% had basal cell carcinoma and 11% had squamous cell carcinoma, both low-and high-risk tumors with varying sizes, locations, and histological subtypes. A safety margin of 3–5 mm is used for excision of low-risk malignancies and 5–10 mm for high-risk cancers. In 17 patients, skin grafts (split-thickness skin grafts and full-thickness skin grafts) are employed. 56 patients underwent local advancement, transposition, and rotational flaps; 15 patients underwent regional interpolation flaps; 6 patients sustained neck lymph node infiltration so they underwent cervical block dissection and distant pedicled flaps as latissimus dorsi muscle flaps; and 4 patients underwent cervical block dissection and free tissue transfer. Six patients experienced problems in the form of two partial graft and flap losses, two wound infections, and one scar retraction; however, with targeted care, they recovered well. Ninety-two percent of patients found the cosmetic outcomes satisfactory, and the functional outcome was good. Wide excision and appropriate surgical reconstruction are ideal treatment modalities and may yield good aesthetic results or functional outcome, also the use of split-thickness skin grafts does not come as a first priority, where a lot of cases could have been treated with local flaps, as demonstrated in this consecutive series of treated patients. Treatment of NMSC on the face required a basic knowledge, presents a challenge to plastic surgeons, and is based on achieving the best oncological, functional, and cosmetic result. It is crucial to emphasize the need of patient education and appropriate tumor monitoring after NMSC therapy. A review of a big series of facial malignancy that may guide further studies cannot be understated.
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