刚果民主共和国桑布瓦盘尾丝虫病的流行病学和临床概况

Lukinga Witanene Jean Paul
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摘要

导言:盘尾丝虫病是导致感染性失明的第二大原因。这种疾病因其眼部并发症而十分严重。这种疾病是由一种特殊的盘尾丝虫(Ochocerca Volvulus)引起的,其传播途径是模拟水域(Mouches blacks circulant autours of the waters at current fast)。我们有 5 种综合征:Cutane、Nodulaire、Oculaire、Lymphatique 和 Neurologique。这些并发症让他看到了 1972 年通过 OMS 获得的 cecite of riviere 的价值。我们的目标是确定盘尾丝虫病在 Sambwa 卫生区的流行概况:我们进行了一项为期 5 个月(01/01 至 01/05/2023)的前瞻性横断面描述性研究。我们将皮肤活检呈盘尾丝虫病阳性、年龄在 10 至 90 岁之间、在桑布瓦居住 10 年以上的患者纳入研究范围。显著性阈值为 0.05%。数据录入和分析使用 Excel、Word 和 IBM SPSS 23 软件。共对 100 人进行了检查,其中 38 人被保留:盘尾丝虫病发病率为 38%,男性居多(57.9%,性别比为 1.4)。平均年龄为 64.37±11.63 岁。农民占 68.4%。大多数患者在桑姆巴瓦居住了 10 至 29 年(42.2%)。眼部综合症占病例的 57.6%,其中以双侧白内障(31.6%)为主,年龄与眼部综合症之间存在关联(P=0.00011)。右眼失明占 31.6%,左眼轻度损伤占 26.3%。眼压在 15.9 至 20.6 mmHg 之间的病例,右眼占 81.6%,左眼占 76.3%。在大多数病例中,眼底无法触及(右眼为 26.3%,左眼为 21.1%)。47.4%的病例存在屈光不正:考虑到我们的研究结果,盘尾丝虫病是一种相对常见的疾病,桑布瓦卫生区属于低流行区。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidemio-Clinical Profile of Onchocerciasis in Sambwa in the Democratic Republic of Congo
Introduction: Onchocerciasis is the second leading cause of infectious blindness. This condition is serious because of its ocular complications. The sickness is caused through a Nematode specifique of I man Ochocerca Volvulus the transmission se made through a vecteur the Simulie (Mouches blacks circulant autours of the waters at current fast). We have 5 Syndroms: Cutane, Nodulaire, Oculaire, Lymphatique and Neurologique. These complications eyes him at valu the name of cecite of riviere through OMS in 1972. Our objective was to determine the epidemiological profile of onchocerciasis in the Sambwa health area. Materials and method: We conducted a prospective cross-sectional descriptive study over a period of 5 months (01/01 to 01/05/2023). We included patients whose skin biopsy was positive for onchocerciasis, aged 10 to 90 years old and having lived more than 10 years in Sambwa. The significance threshold was 0.05%. Excel, Word and IBM SPSS 23 software were used for data entry and analysis. One hundred people were examined, 38 of whom were retained. Results: The frequency of onchocerciasis was 38%, men predominated (57.9%, sex ratio 1.4). The average age was 64.37±11.63 years. Farmers represented 68.4%. Most patients had a stay in Sambwa of 10 to 29 years (42.2%). Ocular syndromes represented 57.6% of cases, of which bilateral cataract (31.6%) predominated, there was an association between age and ocular syndromes (p=0.00011). Blindness represented 31.6% of cases in the right eye while in the left eye mild impairment represented 26.3% of cases. Tonometry between 15.9 and 20.6 mmHg was 81.6% on the right and 76.3% on the left. In most cases the fundus was inaccessible (26.3% on the right and 21.1% on the left). In 47.4% of cases there was a refractive error. Conclusion: Considering our results, onchocerciasis is a relatively common condition, the Sambwa health area is a Hypoendemic area.
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