儿童柳叶刀移植后因淀粉样变性引起的复发性脑内血肿

IF 3.2 Q2 CLINICAL NEUROLOGY
Maša Fabjan, Ana Jurečič, Miha Jerala, Janja Pretnar Oblak, Senta Frol
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引用次数: 0

摘要

由于神经外科手术过程中淀粉样蛋白β的传播而导致的假定先天性脑淀粉样血管病(iCAA)的发表病例数量正在缓慢上升。其中一种潜在的传播途径是在神经外科手术中通过尸体硬脑膜移植(LYODURA)暴露。这是一例 46 岁的女性患者,无慢性疾病,反复出现脑内出血(ICH),无潜在血管病变。四十年前,患者曾接受过一次神经外科手术,并记录有 LYODURA 移植。脑活检证实了 CAA。这是一例罕见的在儿童时期接受过有记录的 LYODURA 移植后经组织学证实的 iCAA 病例。我们的病例和已发表的 iCAA 病例强调,对于可能与 CAA 有关的 ICH 患者,有必要将神经外科手术史作为重要数据加以考虑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recurrent Intracerebral Haematomas Due to Amyloid Angyopathy after Lyodura Transplantation in Childhood.

The number of published cases of presumed iatrogenic cerebral amyloid angiopathy (iCAA) due to the transmission of amyloid β during neurosurgery is slowly rising. One of the potential ways of transmission is through a cadaveric dura mater graft (LYODURA) exposure during neurosurgery. This is a case of a 46-year-old female patient with no chronic conditions who presented with recurrent intracerebral haemorrhages (ICHs) without underlying vessel pathology. Four decades prior, the patient had a neurosurgical procedure with documented LYODURA transplantation. Brain biopsy confirmed CAA. This is a rare case of histologically proven iCAA after a documented LYODURA transplantation in childhood. Our case and already published iCAA cases emphasize the need for considering neurosurgery procedure history as important data in patients who present with ICH possibly related to CAA.

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来源期刊
Neurology International
Neurology International CLINICAL NEUROLOGY-
CiteScore
3.70
自引率
3.30%
发文量
69
审稿时长
11 weeks
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