莫桑比克生产的玉米粉中的黄曲霉毒素及其风险评估。

IF 2.5 3区 农林科学 Q2 CHEMISTRY, APPLIED
Martinho Gamas Dinis Martinho, Andrea Rebouças Rocha, Nathália Ribeiro Dos Santos, Vinícius Silva Pitanga de Jesus, Erival Amorim Gomes Júnior, José Antonio Menezes-Filho
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引用次数: 0

摘要

这项研究调查了莫桑比克生产的玉米面中黄曲霉毒素(B1、B2、G1 和 G2)的含量,并评估了相关的致癌风险。在不同的时间,从五家面粉加工厂收集了 30 份玉米粉样本。这些样品采用高效液相色谱法 (HPLC) 和荧光检测法进行测定。AFB1 浓度介于 0.25 至 0.33 μg kg-1 之间。黄曲霉毒素总含量为 0.55 至 1.05 微克/千克,平均值为 0.89 微克/千克,莫桑比克和欧盟的最高限量分别为 10 微克/千克和 4 微克/千克。计算得出的男性和女性暴露限值分别为 243 微克和 231 微克,比风险临界值低几倍,这表明食用这种玉米面有可能因摄入黄曲霉毒素而患上肝癌,因为黄曲霉毒素是大多数非洲国家的主食。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aflatoxins in maize flour produced in Mozambique and its risk assessment.

This study investigated the occurrence of aflatoxins (B1, B2, G1, and G2) in maize flour produced in Mozambique and to assess the associated carcinogenic risk. At different opportunities, 30 samples of maize flour were collected in five flour processing factories. These were determined by high-performance liquid chromatography (HPLC) with fluorescence detection. AFB1 concentrations ranged from 0.25 to 0.33 μg kg-1. The levels of total aflatoxins ranged from 0.55 to 1.05 μg kg-1, with a mean of 0.89 μg kg-1, for which maximum limits (MLs) are 10 and 4 μg kg-1 for Mozambique and the European Union, respectively. The calculated Margin of Exposure (MOE) for men and women was 243 and 231, respectively, so several folds below the risk cut-off level, indicating that consumption of such maize flour poses a potential risk of hepatocarcinoma related to aflatoxin exposure due to high intake of this food, a staple diet in most African countries.

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来源期刊
CiteScore
5.30
自引率
10.30%
发文量
37
审稿时长
2.7 months
期刊介绍: Food Additives & Contaminants: Part B publishes surveillance data indicating the presence and levels of occurrence of designated food additives, residues and contaminants in foods, food supplements and animal feed. Data using validated methods must meet stipulated quality standards to be acceptable and must be presented in a prescribed format for subsequent data-handling. Food Additives & Contaminants: Part B restricts its scope to include certain classes of food additives, residues and contaminants. This is based on a goal of covering those areas where there is a need to record surveillance data for the purposes of exposure and risk assessment. The scope is initially restricted to: Additives - food colours, artificial sweeteners, and preservatives; Residues – veterinary drug and pesticide residues; Contaminants – metals, mycotoxins, phycotoxins, plant toxins, nitrate/nitrite, PCDDs/PCFDs, PCBs, PAHs, acrylamide, 3-MPCD and contaminants derived from food packaging. Readership: The readership includes scientists involved in all aspects of food safety and quality and particularly those involved in monitoring human exposure to chemicals from the diet. Papers reporting surveillance data in areas other than the above should be submitted to Part A . The scope of Part B will be expanded from time-to-time to ensure inclusion of new areas of concern.
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